Cargando…
Transcription factor induced conversion of human fibroblasts towards the hair cell lineage
Hearing loss is the most common sensorineural disorder, affecting over 5% of the population worldwide. Its most frequent cause is the loss of hair cells (HCs), the mechanosensory receptors of the cochlea. HCs transduce incoming sounds into electrical signals that activate auditory neurons, which in...
Autores principales: | Duran Alonso, María Beatriz, Lopez Hernandez, Iris, de la Fuente, Miguel Angel, Garcia-Sancho, Javier, Giraldez, Fernando, Schimmang, Thomas |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6034836/ https://www.ncbi.nlm.nih.gov/pubmed/29979748 http://dx.doi.org/10.1371/journal.pone.0200210 |
Ejemplares similares
-
Meis2 Is Required for Inner Ear Formation and Proper Morphogenesis of the Cochlea
por: Durán Alonso, María Beatriz, et al.
Publicado: (2021) -
Lineage conversion of mouse fibroblasts to pancreatic α-cells
por: Liu, Tianjin, et al.
Publicado: (2017) -
Signaling and Transcription Factors during Inner Ear Development: The Generation of Hair Cells and Otic Neurons
por: Gálvez, Héctor, et al.
Publicado: (2017) -
Generation of inner ear hair cells by direct lineage conversion of primary somatic cells
por: Menendez, Louise, et al.
Publicado: (2020) -
Mediator 1 ablation induces enamel-to-hair lineage conversion in mice through enhancer dynamics
por: Thaler, Roman, et al.
Publicado: (2023)