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Soluble amyloid-beta buffering by plaques in Alzheimer disease dementia versus high-pathology controls

An unanswered question regarding Alzheimer disease dementia (ADD) is whether amyloid-beta (Aβ) plaques sequester toxic soluble Aβ species early during pathological progression. We previously reported that the concentration of soluble Aβ aggregates from patients with mild dementia was higher than sol...

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Detalles Bibliográficos
Autores principales: Esparza, Thomas J., Gangolli, Mihika, Cairns, Nigel J., Brody, David L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6034844/
https://www.ncbi.nlm.nih.gov/pubmed/29979775
http://dx.doi.org/10.1371/journal.pone.0200251