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Soluble amyloid-beta buffering by plaques in Alzheimer disease dementia versus high-pathology controls
An unanswered question regarding Alzheimer disease dementia (ADD) is whether amyloid-beta (Aβ) plaques sequester toxic soluble Aβ species early during pathological progression. We previously reported that the concentration of soluble Aβ aggregates from patients with mild dementia was higher than sol...
Autores principales: | Esparza, Thomas J., Gangolli, Mihika, Cairns, Nigel J., Brody, David L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6034844/ https://www.ncbi.nlm.nih.gov/pubmed/29979775 http://dx.doi.org/10.1371/journal.pone.0200251 |
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