Polymorphisms and haplotypes in the promoter of the TNF-α gene are associated with disease severity of severe fever with thrombocytopenia syndrome in Chinese Han population

Severe fever with thrombocytopenia syndrome (SFTS) is an emerging infectious disease that is caused by a novel bunyavirus, SFTSV. We assessed whether the single nucleotide polymorphisms (SNPs) in the tumor necrosis factor-alpha (TNF-α) were associated with risk to severity of SFTS. Five TNF-α SNPs (...

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Detalles Bibliográficos
Autores principales: Xing, Bo, Li, Xiao-Kun, Zhang, Shao-Fei, Lu, Qing-Bin, Du, Juan, Zhang, Pan-He, Yang, Zhen-Dong, Cui, Ning, Guo, Chen-Tao, Cao, Wu-Chun, Zhang, Xiao-Ai, Liu, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6034906/
https://www.ncbi.nlm.nih.gov/pubmed/29939989
http://dx.doi.org/10.1371/journal.pntd.0006547

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