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Prevention and management of adverse events of novel agents in multiple myeloma: a consensus of the European Myeloma Network

During the last few years, several new drugs have been introduced for treatment of patients with multiple myeloma, which have significantly improved the treatment outcome. All of these novel substances differ at least in part in their mode of action from similar drugs of the same drug class, or are...

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Autores principales: Ludwig, Heinz, Delforge, Michel, Facon, Thierry, Einsele, Hermann, Gay, Francesca, Moreau, Philippe, Avet-Loiseau, Hervé, Boccadoro, Mario, Hajek, Roman, Mohty, Mohamad, Cavo, Michele, Dimopoulos, Meletios A, San-Miguel, Jesús F, Terpos, Evangelos, Zweegman, Sonja, Garderet, Laurent, Mateos, María-Victoria, Cook, Gordon, Leleu, Xavier, Goldschmidt, Hartmut, Jackson, Graham, Kaiser, Martin, Weisel, Katja, van de Donk, Niels W. C. J., Waage, Anders, Beksac, Meral, Mellqvist, Ulf H., Engelhardt, Monika, Caers, Jo, Driessen, Christoph, Bladé, Joan, Sonneveld, Pieter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6035147/
https://www.ncbi.nlm.nih.gov/pubmed/29720735
http://dx.doi.org/10.1038/s41375-018-0040-1
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author Ludwig, Heinz
Delforge, Michel
Facon, Thierry
Einsele, Hermann
Gay, Francesca
Moreau, Philippe
Avet-Loiseau, Hervé
Boccadoro, Mario
Hajek, Roman
Mohty, Mohamad
Cavo, Michele
Dimopoulos, Meletios A
San-Miguel, Jesús F
Terpos, Evangelos
Zweegman, Sonja
Garderet, Laurent
Mateos, María-Victoria
Cook, Gordon
Leleu, Xavier
Goldschmidt, Hartmut
Jackson, Graham
Kaiser, Martin
Weisel, Katja
van de Donk, Niels W. C. J.
Waage, Anders
Beksac, Meral
Mellqvist, Ulf H.
Engelhardt, Monika
Caers, Jo
Driessen, Christoph
Bladé, Joan
Sonneveld, Pieter
author_facet Ludwig, Heinz
Delforge, Michel
Facon, Thierry
Einsele, Hermann
Gay, Francesca
Moreau, Philippe
Avet-Loiseau, Hervé
Boccadoro, Mario
Hajek, Roman
Mohty, Mohamad
Cavo, Michele
Dimopoulos, Meletios A
San-Miguel, Jesús F
Terpos, Evangelos
Zweegman, Sonja
Garderet, Laurent
Mateos, María-Victoria
Cook, Gordon
Leleu, Xavier
Goldschmidt, Hartmut
Jackson, Graham
Kaiser, Martin
Weisel, Katja
van de Donk, Niels W. C. J.
Waage, Anders
Beksac, Meral
Mellqvist, Ulf H.
Engelhardt, Monika
Caers, Jo
Driessen, Christoph
Bladé, Joan
Sonneveld, Pieter
author_sort Ludwig, Heinz
collection PubMed
description During the last few years, several new drugs have been introduced for treatment of patients with multiple myeloma, which have significantly improved the treatment outcome. All of these novel substances differ at least in part in their mode of action from similar drugs of the same drug class, or are representatives of new drug classes, and as such present with very specific side effect profiles. In this review, we summarize these adverse events, provide information on their prevention, and give practical guidance for monitoring of patients and for management of adverse events.
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spelling pubmed-60351472018-07-09 Prevention and management of adverse events of novel agents in multiple myeloma: a consensus of the European Myeloma Network Ludwig, Heinz Delforge, Michel Facon, Thierry Einsele, Hermann Gay, Francesca Moreau, Philippe Avet-Loiseau, Hervé Boccadoro, Mario Hajek, Roman Mohty, Mohamad Cavo, Michele Dimopoulos, Meletios A San-Miguel, Jesús F Terpos, Evangelos Zweegman, Sonja Garderet, Laurent Mateos, María-Victoria Cook, Gordon Leleu, Xavier Goldschmidt, Hartmut Jackson, Graham Kaiser, Martin Weisel, Katja van de Donk, Niels W. C. J. Waage, Anders Beksac, Meral Mellqvist, Ulf H. Engelhardt, Monika Caers, Jo Driessen, Christoph Bladé, Joan Sonneveld, Pieter Leukemia Review Article During the last few years, several new drugs have been introduced for treatment of patients with multiple myeloma, which have significantly improved the treatment outcome. All of these novel substances differ at least in part in their mode of action from similar drugs of the same drug class, or are representatives of new drug classes, and as such present with very specific side effect profiles. In this review, we summarize these adverse events, provide information on their prevention, and give practical guidance for monitoring of patients and for management of adverse events. Nature Publishing Group UK 2018-05-02 2018 /pmc/articles/PMC6035147/ /pubmed/29720735 http://dx.doi.org/10.1038/s41375-018-0040-1 Text en © The Author(s) 2018 Open Access This article is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License, which permits any non-commercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. If you remix, transform, or build upon this article or a part thereof, you must distribute your contributions under the same license as the original. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-sa/4.0/.
spellingShingle Review Article
Ludwig, Heinz
Delforge, Michel
Facon, Thierry
Einsele, Hermann
Gay, Francesca
Moreau, Philippe
Avet-Loiseau, Hervé
Boccadoro, Mario
Hajek, Roman
Mohty, Mohamad
Cavo, Michele
Dimopoulos, Meletios A
San-Miguel, Jesús F
Terpos, Evangelos
Zweegman, Sonja
Garderet, Laurent
Mateos, María-Victoria
Cook, Gordon
Leleu, Xavier
Goldschmidt, Hartmut
Jackson, Graham
Kaiser, Martin
Weisel, Katja
van de Donk, Niels W. C. J.
Waage, Anders
Beksac, Meral
Mellqvist, Ulf H.
Engelhardt, Monika
Caers, Jo
Driessen, Christoph
Bladé, Joan
Sonneveld, Pieter
Prevention and management of adverse events of novel agents in multiple myeloma: a consensus of the European Myeloma Network
title Prevention and management of adverse events of novel agents in multiple myeloma: a consensus of the European Myeloma Network
title_full Prevention and management of adverse events of novel agents in multiple myeloma: a consensus of the European Myeloma Network
title_fullStr Prevention and management of adverse events of novel agents in multiple myeloma: a consensus of the European Myeloma Network
title_full_unstemmed Prevention and management of adverse events of novel agents in multiple myeloma: a consensus of the European Myeloma Network
title_short Prevention and management of adverse events of novel agents in multiple myeloma: a consensus of the European Myeloma Network
title_sort prevention and management of adverse events of novel agents in multiple myeloma: a consensus of the european myeloma network
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6035147/
https://www.ncbi.nlm.nih.gov/pubmed/29720735
http://dx.doi.org/10.1038/s41375-018-0040-1
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