Co-treatment of TGF-β3 and BMP7 is superior in stimulating chondrocyte redifferentiation in both hypoxia and normoxia compared to single treatments

Signaling by members of the transforming growth factor-β (TGF-β) superfamily, such as TGF-β3 and BMP7, and oxygen tension play a pivotal role in chondrocyte biology. The objective of this research was to investigate the endogenous BMP7 expression in human osteoarthritis (OA) cartilage and the effect...

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Detalles Bibliográficos
Autores principales: Huang, Xiaobin, Zhong, Leilei, Post, Janine N., Karperien, Marcel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6035177/
https://www.ncbi.nlm.nih.gov/pubmed/29980690
http://dx.doi.org/10.1038/s41598-018-27602-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6035177/
https://www.ncbi.nlm.nih.gov/pubmed/29980690
http://dx.doi.org/10.1038/s41598-018-27602-y

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