Intermedin protects against sepsis by concurrently re-establishing the endothelial barrier and alleviating inflammatory responses

Sepsis is a life-threatening condition caused by dysregulated host responses to infection. Widespread vascular hyperpermeability and a “cytokine storm” are two pathophysiological hallmarks of sepsis. Here, we show that intermedin (IMD), a member of the calcitonin family, alleviates organ injury and...

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Detalles Bibliográficos
Autores principales: Xiao, Fei, Wang, Denian, Kong, Lingmiao, Li, Min, Feng, Zhongxue, Shuai, Bingxing, Wang, Lijun, Wei, Yong’gang, Li, Hongyu, Wu, Sisi, Tan, Chun, Zhao, Huan, Hu, Xuejiao, Liu, Jin, Kang, Yan, Liao, Xuelian, Zhou, Yan, Zhang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6035189/
https://www.ncbi.nlm.nih.gov/pubmed/29980671
http://dx.doi.org/10.1038/s41467-018-05062-2

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