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Naturally derived Heme-Oxygenase 1 inducers attenuate inflammatory responses in human dendritic cells and T cells: relevance for psoriasis treatment

Psoriasis is a chronic autoimmune disease mediated by dysregulated immune responses in dendritic cells (DC) and T cells. The stress-response enzyme heme oxygenase-1 (HO-1) has been described as protective in animal models of psoriasis, however, implementation of HO-1-based therapies is hindered by t...

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Detalles Bibliográficos
Autores principales: Campbell, Nicole K., Fitzgerald, Hannah K., Malara, Anna, Hambly, Roisin, Sweeney, Cheryl M., Kirby, Brian, Fletcher, Jean M., Dunne, Aisling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6035209/
https://www.ncbi.nlm.nih.gov/pubmed/29980703
http://dx.doi.org/10.1038/s41598-018-28488-6