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Evolutionary trade-offs associated with loss of PmrB function in host-adapted Pseudomonas aeruginosa

Pseudomonas aeruginosa colonises the upper airway of cystic fibrosis (CF) patients, providing a reservoir of host-adapted genotypes that subsequently establish chronic lung infection. We previously experimentally-evolved P. aeruginosa in a murine model of respiratory tract infection and observed ear...

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Detalles Bibliográficos
Autores principales:	Bricio-Moreno, Laura, Sheridan, Victoria H., Goodhead, Ian, Armstrong, Stuart, Wong, Janet K.L., Waters, Elaine M., Sarsby, Joscelyn, Panagiotou, Stavros, Dunn, James, Chakraborty, Adrita, Fang, Yongliang, Griswold, Karl E., Winstanley, Craig, Fothergill, Joanne L., Kadioglu, Aras, Neill, Daniel R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6035264/ https://www.ncbi.nlm.nih.gov/pubmed/29980663 http://dx.doi.org/10.1038/s41467-018-04996-x

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