Human ISL1(+) Ventricular Progenitors Self-Assemble into an In Vivo Functional Heart Patch and Preserve Cardiac Function Post Infarction

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The generation of human pluripotent stem cell (hPSC)-derived ventricular progenitors and their assembly into a 3-dimensional in vivo functional ventricular heart patch has remained an elusive goal. Herein, we report the generation of an enriched pool of hPSC-derived ventricular progenitors (HVPs), w...

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Detalles Bibliográficos
Autores principales: Foo, Kylie S., Lehtinen, Miia L., Leung, Chuen Yan, Lian, Xiaojun, Xu, Jiejia, Keung, Wendy, Geng, Lin, Kolstad, Terje R.S., Thams, Sebastian, Wong, Andy On-tik, Wong, Nicodemus, Bylund, Kristine, Zhou, Chikai, He, Xiaobing, Jin, Shao-Bo, Clarke, Jonathan, Lendahl, Urban, Li, Ronald A., Louch, William E., Chien, Kenneth R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6035340/
https://www.ncbi.nlm.nih.gov/pubmed/29606507
http://dx.doi.org/10.1016/j.ymthe.2018.02.012
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