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The Association Between Empirical Dietary Inflammatory Pattern and Metabolic Phenotypes in Overweight/Obese Adults

OBJECTIVES: The study aimed to investigate whether diet-induced inflammation assessed by Empirical Dietary Inflammatory Pattern (EDIP) is associated with odds of unhealthy metabolic phenotype and components of metabolic syndrome (MetS). METHODS: This cross-sectional study included 403 overweight/obe...

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Autores principales: Soltani, Sepideh, Moslehi, Nazanin, Hosseini-Esfahani, Firoozeh, Vafa, Mohammadreza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Kowsar 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6035353/
https://www.ncbi.nlm.nih.gov/pubmed/30008758
http://dx.doi.org/10.5812/ijem.60048
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author Soltani, Sepideh
Moslehi, Nazanin
Hosseini-Esfahani, Firoozeh
Vafa, Mohammadreza
author_facet Soltani, Sepideh
Moslehi, Nazanin
Hosseini-Esfahani, Firoozeh
Vafa, Mohammadreza
author_sort Soltani, Sepideh
collection PubMed
description OBJECTIVES: The study aimed to investigate whether diet-induced inflammation assessed by Empirical Dietary Inflammatory Pattern (EDIP) is associated with odds of unhealthy metabolic phenotype and components of metabolic syndrome (MetS). METHODS: This cross-sectional study included 403 overweight/obese individuals recruited from employees of two pharmaceutical companies in Iran. The weighted intake of 15 food groups was summed to construct EDIP and metabolic phenotypes were defined based on MetS criteria. RESULTS: After adjusting for age, sex, BMI, and marital status, the odds of unhealthy phenotype increased significantly from quartile 1 to quartile 4 (P-trend = 0.013). However, the association became non-significant after adjusting for energy intake. Compared to those in the lowest quartile, individuals with higher EDIP scores had higher odds of high fasting blood sugar (FBS) (P-trend = 0.031) and low HDL-C (P-trend = 0.036) after adjusting for all covariates. By adding energy intake into the model, an inverse association was observed between EDIP, waist circumference (WC), and odds of high WC. CONCLUSIONS: A higher pro-inflammatory diet was associated with higher odds of unhealthy phenotype, high FBS, and low-HDL-C in overweight/obese individuals. However, the association with unhealthy phenotype seems to be dependent on the energy intake.
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spelling pubmed-60353532018-07-13 The Association Between Empirical Dietary Inflammatory Pattern and Metabolic Phenotypes in Overweight/Obese Adults Soltani, Sepideh Moslehi, Nazanin Hosseini-Esfahani, Firoozeh Vafa, Mohammadreza Int J Endocrinol Metab Research Article OBJECTIVES: The study aimed to investigate whether diet-induced inflammation assessed by Empirical Dietary Inflammatory Pattern (EDIP) is associated with odds of unhealthy metabolic phenotype and components of metabolic syndrome (MetS). METHODS: This cross-sectional study included 403 overweight/obese individuals recruited from employees of two pharmaceutical companies in Iran. The weighted intake of 15 food groups was summed to construct EDIP and metabolic phenotypes were defined based on MetS criteria. RESULTS: After adjusting for age, sex, BMI, and marital status, the odds of unhealthy phenotype increased significantly from quartile 1 to quartile 4 (P-trend = 0.013). However, the association became non-significant after adjusting for energy intake. Compared to those in the lowest quartile, individuals with higher EDIP scores had higher odds of high fasting blood sugar (FBS) (P-trend = 0.031) and low HDL-C (P-trend = 0.036) after adjusting for all covariates. By adding energy intake into the model, an inverse association was observed between EDIP, waist circumference (WC), and odds of high WC. CONCLUSIONS: A higher pro-inflammatory diet was associated with higher odds of unhealthy phenotype, high FBS, and low-HDL-C in overweight/obese individuals. However, the association with unhealthy phenotype seems to be dependent on the energy intake. Kowsar 2018-03-12 /pmc/articles/PMC6035353/ /pubmed/30008758 http://dx.doi.org/10.5812/ijem.60048 Text en Copyright © 2018, International Journal of Endocrinology and Metabolism http://creativecommons.org/licenses/by-nc/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited
spellingShingle Research Article
Soltani, Sepideh
Moslehi, Nazanin
Hosseini-Esfahani, Firoozeh
Vafa, Mohammadreza
The Association Between Empirical Dietary Inflammatory Pattern and Metabolic Phenotypes in Overweight/Obese Adults
title The Association Between Empirical Dietary Inflammatory Pattern and Metabolic Phenotypes in Overweight/Obese Adults
title_full The Association Between Empirical Dietary Inflammatory Pattern and Metabolic Phenotypes in Overweight/Obese Adults
title_fullStr The Association Between Empirical Dietary Inflammatory Pattern and Metabolic Phenotypes in Overweight/Obese Adults
title_full_unstemmed The Association Between Empirical Dietary Inflammatory Pattern and Metabolic Phenotypes in Overweight/Obese Adults
title_short The Association Between Empirical Dietary Inflammatory Pattern and Metabolic Phenotypes in Overweight/Obese Adults
title_sort association between empirical dietary inflammatory pattern and metabolic phenotypes in overweight/obese adults
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6035353/
https://www.ncbi.nlm.nih.gov/pubmed/30008758
http://dx.doi.org/10.5812/ijem.60048
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