Quantitative Analysis Reveals that Actin and Src-Family Kinases Regulate Nuclear YAP1 and Its Export

The transcriptional regulator YAP1 is critical for the pathological activation of fibroblasts. In normal fibroblasts, YAP1 is located in the cytoplasm, while in activated cancer-associated fibroblasts, it is nuclear and promotes the expression of genes required for pro-tumorigenic functions. Here, w...

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Detalles Bibliográficos
Autores principales: Ege, Nil, Dowbaj, Anna M., Jiang, Ming, Howell, Michael, Hooper, Steven, Foster, Charles, Jenkins, Robert P., Sahai, Erik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6035388/
https://www.ncbi.nlm.nih.gov/pubmed/29909276
http://dx.doi.org/10.1016/j.cels.2018.05.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6035388/
https://www.ncbi.nlm.nih.gov/pubmed/29909276
http://dx.doi.org/10.1016/j.cels.2018.05.006

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