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Characterization of temperature-sensitive leak K(+) currents and expression of TRAAK, TREK-1, and TREK2 channels in dorsal root ganglion neurons of rats
Leak K(+) currents are mediated by two-pore domain K(+) (K2P) channels and are involved in controlling neuronal excitability. Of 15 members of K2P channels cloned so far, TRAAK, TREK-1, and TREK-2 are temperature sensitive. In the present study, we show that strong immunoreactivity of TRAAK, TREK-1...
Autores principales: | Viatchenko-Karpinski, Viacheslav, Ling, Jennifer, Gu, Jianguo G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6035395/ https://www.ncbi.nlm.nih.gov/pubmed/29980241 http://dx.doi.org/10.1186/s13041-018-0384-5 |
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