Dual inhibition of sodium–glucose linked cotransporters 1 and 2 exacerbates cardiac dysfunction following experimental myocardial infarction

BACKGROUND: Inhibiting both type 1 and 2 sodium–glucose linked cotransporter (SGLT1/2) offers the potential to not only increase glucosuria beyond that seen with selective SGLT2 inhibition alone but to reduce glucose absorption from the gut and to thereby also stimulate glucagon-like peptide 1 secre...

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Detalles Bibliográficos
Autores principales: Connelly, Kim A., Zhang, Yanling, Desjardins, Jean-François, Thai, Kerri, Gilbert, Richard E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6035399/
https://www.ncbi.nlm.nih.gov/pubmed/29981571
http://dx.doi.org/10.1186/s12933-018-0741-9

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