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Efficacy of Hydroxy-L-proline (HYP) analogs in the treatment of primary hyperoxaluria in Drosophila Melanogaster

BACKGROUND: Substrate reduction therapy with analogs reduces the accumulation of substrates by inhibiting the metabolic pathways involved in their biosynthesis, providing new treatment options for patients with primary hyperoxalurias (PHs) that often progress to end-stage renal disease (ESRD). This...

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Detalles Bibliográficos
Autores principales:	Yang, Huan, Male, Musa, Li, Yang, Wang, Ning, Zhao, Chenming, Jin, Shan, Hu, Juncheng, Chen, Zhiqiang, Ye, Zhangqun, Xu, Hua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6035412/ https://www.ncbi.nlm.nih.gov/pubmed/29980178 http://dx.doi.org/10.1186/s12882-018-0980-8

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