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PD-1 deficiency promotes TFH cells expansion in ITV-immunized mice by upregulating cytokines secretion

BACKGROUND: T follicular helper (TFH) cells are fundamental for the development of humoral immunity. In our previous study, we found that PD-1 deficiency substantially promoted the expansion of Plasmodium-specific TFH cells and enhanced the humoral immunity of ITV (infection treatment vaccine)-immun...

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Detalles Bibliográficos
Autores principales:	Liu, Taiping, Cheng, Xiangyun, Ding, Yan, Zhu, Feng, Fu, Yong, Peng, Xiaohong, Xu, Wenyue
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6035468/ https://www.ncbi.nlm.nih.gov/pubmed/29980219 http://dx.doi.org/10.1186/s13071-018-2984-4

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