Inhibition of Glycogen Synthase II with RNAi Prevents Liver Injury in Mouse Models of Glycogen Storage Diseases

Glycogen storage diseases (GSDs) of the liver are devastating disorders presenting with fasting hypoglycemia as well as hepatic glycogen and lipid accumulation, which could lead to long-term liver damage. Diet control is frequently utilized to manage the potentially dangerous hypoglycemia, but there...

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Detalles Bibliográficos
Autores principales: Pursell, Natalie, Gierut, Jessica, Zhou, Wei, Dills, Michael, Diwanji, Rohan, Gjorgjieva, Monika, Saxena, Utsav, Yang, Jr-Shiuan, Shah, Anee, Venkat, Nandini, Storr, Rachel, Kim, Boyoung, Wang, Weimin, Abrams, Marc, Raffin, Margaux, Mithieux, Gilles, Rajas, Fabienne, Dudek, Henryk, Brown, Bob D., Lai, Chengjung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6035741/
https://www.ncbi.nlm.nih.gov/pubmed/29784585
http://dx.doi.org/10.1016/j.ymthe.2018.04.023

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