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FMR1 expression in human granulosa cells increases with exon 1 CGG repeat length depending on ovarian reserve

BACKGROUND: Fragile-X-Mental-Retardation-1- (FMR1)-gene is supposed to be a key gene for ovarian reserve and folliculogenesis. It contains in its 5’-UTR a triplet-base-repeat (CGG), that varies between 26 and 34 in general population. CGG-repeat-lengths with 55–200 repeats (pre-mutation = PM) show i...

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Detalles Bibliográficos
Autores principales:	Rehnitz, Julia, Alcoba, Diego D., Brum, Ilma S., Dietrich, Jens E., Youness, Berthe, Hinderhofer, Katrin, Messmer, Birgitta, Freis, Alexander, Strowitzki, Thomas, Germeyer, Ariane
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6035797/ https://www.ncbi.nlm.nih.gov/pubmed/29981579 http://dx.doi.org/10.1186/s12958-018-0383-5

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