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The replicative senescent mesenchymal stem / stromal cells defect in DNA damage response and anti-oxidative capacity

Replicative senescence and potential malignant transformation are great limitations in the clinical application of bone marrow-derived mesenchymal stem / stromal cells (MSCs). An abnormal DNA damage response may result in genomic instability, which is an integral component of aging and tumorigenesis...

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Detalles Bibliográficos
Autores principales:	Yu, Jin, Shi, Jiazhong, Zhang, Yue, Zhang, Yi, Huang, Yaqin, Chen, Zhiwen, Yang, Jin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2018
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6036081/ https://www.ncbi.nlm.nih.gov/pubmed/30008586 http://dx.doi.org/10.7150/ijms.24635

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