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Effects of Tranexamic Acid Based on its Population Pharmacokinetics in Pediatric Patients Undergoing Distraction Osteogenesis for Craniosynostosis: Rotational Thromboelastometry (ROTEM(TM)) Analysis

Background: Distraction osteogenesis for craniosynostosis is associated with significant hemorrhage. Additionally, patients usually require several transfusions. Tranexamic acid (TXA) is effective for reducing blood loss and the need for transfusions during surgeries. However, the significance of TX...

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Detalles Bibliográficos
Autores principales: Kim, Eun Jung, Kim, Yong Oock, Shim, Kyu Won, Ko, Byung Woong, Lee, Jong Wha, Koo, Bon-Nyeo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6036088/
https://www.ncbi.nlm.nih.gov/pubmed/30008588
http://dx.doi.org/10.7150/ijms.25008