Cargando…

Morphine Induces Fibroblast Activation through Up-regulation of Connexin 43 Expression: Implication of Fibrosis in Wound Healing

Morphine is the most effective drugs for attenuating various types of severe pain, but morphine abuse carries a high risk of systemic fibrosis. Our previous have indicated that systemic administration of morphine hinders angiogenesis and delays wound healing. Here we have explained the pathological...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wu, Ping-Ching, Hsu, Wen-Li, Chen, Chun-Lin, Lam, Chen-Fuh, Huang, Yaw-Bin, Huang, Chien-Chi, Lin, Ming-Hong, Lin, Ming-Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2018
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6036091/ https://www.ncbi.nlm.nih.gov/pubmed/30008599 http://dx.doi.org/10.7150/ijms.23074

Ejemplares similares

Expression and Function of Connexin 43 in Human Gingival Wound Healing and Fibroblasts
por: Tarzemany, Rana, et al.
Publicado: (2015)

Connexin 43-Based Therapeutics for Dermal Wound Healing
por: Montgomery, Jade, et al.
Publicado: (2018)

Connexin 43 Hemichannels Regulate the Expression of Wound Healing-Associated Genes in Human Gingival Fibroblasts
por: Tarzemany, Rana, et al.
Publicado: (2017)

Connexin43 Hemichannel-Mediated Regulation of Connexin43
por: Li, Kai, et al.
Publicado: (2013)

Effect of connexin 43 inhibition by the mimetic peptide Gap27 on corneal wound healing, inflammation and neovascularization
por: Elbadawy, Hossein Mostafa, et al.
Publicado: (2016)

Fibrosis, Connexin-43, and Conduction Abnormalities in the Brugada Syndrome
por: Nademanee, Koonlawee, et al.
Publicado: (2015)

Fraxin Promotes the Activation of Nrf2/ARE Pathway via Increasing the Expression of Connexin43 to Ameliorate Diabetic Renal Fibrosis
por: Chen, Rui, et al.
Publicado: (2022)

Connexin43 enhances the expression of osteoarthritis-associated genes in synovial fibroblasts in culture
por: Gupta, Aditi, et al.
Publicado: (2014)

K(ATP) channel agonists preserve connexin43 protein in infarcted rats by a protein kinase C-dependent pathway
por: Lee, Tsung-Ming, et al.
Publicado: (2012)

Connexin 37 and Connexin 43 genotypes in correlation to cytokines in induced sputum and blood in cystic fibrosis (CF)
por: Ludwig, M, et al.
Publicado: (2014)

The Connexin Mimetic Peptide Gap27 and Cx43-Knockdown Reveal Differential Roles for Connexin43 in Wound Closure Events in Skin Model Systems
por: Faniku, Chrysovalantou, et al.
Publicado: (2018)

Squid Ink Polysaccharides Protect Human Fibroblast Against Oxidative Stress by Regulating NADPH Oxidase and Connexin43
por: Chen, Ying, et al.
Publicado: (2020)

Connexin 26 and Connexin 43 in Canine Mammary Carcinoma
por: Luu, Savannah, et al.
Publicado: (2019)

AGE-BSA down-regulates endothelial connexin43 gap junctions
por: Wang, Chi-Young, et al.
Publicado: (2011)

Function of Connexin-43 in Macrophages
por: Rodjakovic, Daniel, et al.
Publicado: (2021)

Dexmedetomidine Exerted Anti-arrhythmic Effects in Rat With Ischemic Cardiomyopathy via Upregulation of Connexin 43 and Reduction of Fibrosis and Inflammation
por: Wu, Shu-jie, et al.
Publicado: (2020)

The inhibition of indoleamine 2, 3-dioxygenase 1 by connexin 43
por: Lin, Han-Chen, et al.
Publicado: (2017)

The Role of Connexins in Wound Healing and Repair: Novel Therapeutic Approaches
por: Wong, Pui, et al.
Publicado: (2016)

Glycated serum albumin decreases connexin 43 phosphorylation in the corpus cavernosum
por: Huang, Yanping, et al.
Publicado: (2022)

Activating Connexin43 gap junctions primes adipose tissue for therapeutic intervention
por: Zhu, Yi, et al.
Publicado: (2022)

Effects of Rutin on Wound Healing in Hyperglycemic Rats
por: Chen, Li-You, et al.
Publicado: (2020)

Connexin 43 Phosphorylation: Implications in Multiple Diseases
por: Zhang, Meng, et al.
Publicado: (2023)

Connexin 43: An Interface Connecting Neuroinflammation to Depression
por: Jiang, Hong, et al.
Publicado: (2023)

Role of CAPE on cardiomyocyte protection via connexin 43 regulation under hypoxia
por: Chen, Chien-Cheng, et al.
Publicado: (2016)

Expression of connexin 43 protein in cardiomyocytes of heart failure mouse model
por: Liu, Shaoyan, et al.
Publicado: (2022)

Internal translation of the connexin 43 transcript
por: Salat-Canela, Clàudia, et al.
Publicado: (2014)

The Role of Connexin 43 in Lung Disease
por: Swartzendruber, Julie A., et al.
Publicado: (2020)

Mechanism of Regulatory Effect of MicroRNA-206 on Connexin 43 in Distant Metastasis of Breast Cancer
por: Lin, Zi-Jing, et al.
Publicado: (2016)

Mechanisms underlying pathological scarring by fibroblasts during wound healing
por: Ma, Yizhao, et al.
Publicado: (2023)

Both PKA and Epac Pathways Mediate N-Acetylcysteine-Induced Connexin43 Preservation in Rats with Myocardial Infarction
por: Lee, Tsung-Ming, et al.
Publicado: (2013)

Connexin 43 plays a role in proliferation and migration of pulmonary arterial fibroblasts in response to hypoxia
por: McNair, Andrew J., et al.
Publicado: (2020)

Connexin 43 reduces susceptibility to sympathetic atrial fibrillation
por: Luo, Beibei, et al.
Publicado: (2021)

ZIP1(+) fibroblasts protect lung cancer against chemotherapy via connexin-43 mediated intercellular Zn(2+) transfer
por: Ni, Chen, et al.
Publicado: (2022)

Fibroblasts and myofibroblasts in wound healing
por: Darby, Ian A, et al.
Publicado: (2014)

Correlation between connexin 43 expression in circulating tumor cells and biological characteristics of breast cancer
por: Wang, Dan-Qing, et al.
Publicado: (2023)

Occludin and connexin 43 expression contribute to the pathogenesis of traumatic brain edema
por: Ren, Wanyin, et al.
Publicado: (2013)

Ginkgo suppresses atherosclerosis through downregulating the expression of connexin 43 in rabbits
por: Wei, Jian Ming, et al.
Publicado: (2013)

Deficiency of cyclase-associated protein 2 promotes arrhythmias associated with connexin43 maldistribution and fibrosis
por: Stöckigt, Florian, et al.
Publicado: (2016)

Fluoxetin Upregulates Connexin 43 Expression in Astrocyte
por: Mostafavi, Hossein, et al.
Publicado: (2014)

Connexin 43 impacts on mitochondrial potassium uptake
por: Boengler, Kerstin, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_b1q6i0qj1rau12qcg669ukd007