Cargando…

A high frequency of CD8(+)CD28(-) T-suppressor cells contributes to maintaining stable graft function and reducing immunosuppressant dosage after liver transplantation

CD8(+)CD28(-)T cells (CD8Ts) exert immunosuppressive effects in various autoimmune diseases. The current study was designed to investigate the role of defects in CD8Ts in liver transplantation (LT). The proportion of CD8Ts in peripheral blood was determined by flow cytometry. The mean proportion of...

Descripción completa

Detalles Bibliográficos
Autores principales:	Geng, Lei, Liu, Jingfeng, Huang, Junjie, Lin, Bingyi, Yu, Songfeng, Shen, Tian, Wang, Zhuoyi, Yang, Zhe, Zhou, Lin, Zheng, Shuseng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2018
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6036103/ https://www.ncbi.nlm.nih.gov/pubmed/30008601 http://dx.doi.org/10.7150/ijms.24042

Ejemplares similares

Lenalidomide overcomes the immunosuppression of regulatory CD8(+)CD28(−) T-cells
por: Neuber, Brigitte, et al.
Publicado: (2017)

CD28(−) and CD28(low)CD8(+) Regulatory T Cells: Of Mice and Men
por: Vuddamalay, Yirajen, et al.
Publicado: (2017)

TGF-β1 maintains suppressor function and Foxp3 expression in CD4(+)CD25(+) regulatory T cells
por: Marie, Julien C., et al.
Publicado: (2005)

Effects of conventional immunosuppressive treatment on CD244+ (CD28null) and FOXP3+ T cells in the inflamed muscle of patients with polymyositis and dermatomyositis
por: Pandya, Jayesh M., et al.
Publicado: (2016)

CD28 engagement inhibits CD73-mediated regulatory activity of CD8(+) T cells
por: Lai, Yo-Ping, et al.
Publicado: (2021)

Graft versus host disease in humanized mice is differentially controlled by CD28 and CD80/86 antagonists
por: Poirier, Nicolas, et al.
Publicado: (2012)

Decreased CD8(+)CD28(+)/CD8(+)CD28(–) T cell ratio can sensitively predict poor outcome for patients with complicated Crohn disease
por: Dai, Shi-xue, et al.
Publicado: (2017)

Single CD28 stimulation induces stable and polyclonal expansion of human regulatory T cells
por: He, Xuehui, et al.
Publicado: (2017)

CD4+CD25+CD127-Foxp3+ and CD8+CD28- Tregs in Renal Transplant Recipients: Phenotypic Patterns, Association With Immunosuppressive Drugs, and Interaction With Effector CD8+ T Cells and CD19+IL-10+ Bregs
por: Aly, Mostafa G., et al.
Publicado: (2021)

Impact of Cytomegalovirus and Grafts versus Host Disease on the Dynamics of CD57+CD28−CD8+ T Cells After Bone Marrow Transplant
por: Mendes, Ana Verena Almeida, et al.
Publicado: (2008)

The CD28-Transmembrane Domain Mediates Chimeric Antigen Receptor Heterodimerization With CD28
por: Muller, Yannick D., et al.
Publicado: (2021)

CD103 spurs on suppressors
por: Van Epps, Heather L.
Publicado: (2005)

Immunosuppressive role of CD11b(+)CD33(+)HLA‐DR(−) myeloid‐derived suppressor cells‐like blast subpopulation in acute myeloid leukemia
por: Hyun, Shin Young, et al.
Publicado: (2020)

CD3(+)CD8(+)CD28(−) T Lymphocytes in Patients with Lupus Nephritis
por: Żabińska, Marcelina, et al.
Publicado: (2016)

The Role of CD28 and CD8(+) T Cells in Keloid Development
por: Shan, Mengjie, et al.
Publicado: (2022)

Certified Professionals: Cd4(+)Cd25(+) Suppressor T Cells
por: Shevach, Ethan M.
Publicado: (2001)

CD98-induced CD147 signaling stabilizes the Foxp3 protein to maintain tissue homeostasis
por: Geng, JieJie, et al.
Publicado: (2021)

Restoration of CD28 Expression in CD28(−) CD8(+) Memory Effector T Cells Reconstitutes Antigen-induced IL-2 Production
por: Topp, Max S., et al.
Publicado: (2003)

Stimulation of CD28 triggers an association between CD28 and phosphatidylinositol 3-kinase in Jurkat T cells
Publicado: (1994)

Association of CD28 IVS3 +17T/C Polymorphism with Soluble CD28 in Rheumatoid Arthritis
por: Ledezma-Lozano, I. Y., et al.
Publicado: (2011)

Human CD8(+)CD28(−) T Suppressor Cells Expanded by IL-15 In Vitro Suppress in an Allospecific and Programmed Cell Death Protein 1-Dependent Manner
por: Feng, Fu, et al.
Publicado: (2018)

Human CD8(+)CD28(−) T suppressor cells expanded by common gamma chain (γc) cytokines retain steady allospecific suppressive capacity in vivo
por: Liu, Guihuan, et al.
Publicado: (2020)

Chimeric CTLA4-CD28-CD3z T Cells Potentiate Antitumor Activity Against CD80/CD86–Positive B Cell Malignancies
por: Lin, Shouheng, et al.
Publicado: (2021)

CTLA-4-Tg/CD-28-KO Mice Exhibit Reduced T Cell Proliferation in vivo Compared to CD-28-KO Mice in a Graft-versus-host Disease Model
por: Yoo, Jong-Sun, et al.
Publicado: (2012)

CD28, Costimulator or Agonist Receptor?
por: Margulies, David H.
Publicado: (2003)

Expression of IL-37 contributes to the immunosuppressive property of human CD4(+)CD25(+) regulatory T cells
por: Shuai, Xu, et al.
Publicado: (2015)

The expansion of CD4(+)CD28(- )T cells in patients with rheumatoid arthritis
por: Pawlik, Andrzej, et al.
Publicado: (2003)

Circulating cytotoxic CD8(+) CD28(-) T cells in ankylosing spondylitis
por: Schirmer, Michael, et al.
Publicado: (2002)

Divide, Conquer, and Sense: CD8(+)CD28(−) T Cells in Perspective
por: Arosa, Fernando A., et al.
Publicado: (2017)

In vivo therapeutic potential of Inula racemosa in hepatic ischemia–reperfusion injury following orthotopic liver transplantation in male albino rats
por: Wang, Zhuoyi, et al.
Publicado: (2017)

CD20(+)CD22(+)ADAM28(+) B Cells in Tertiary Lymphoid Structures Promote Immunotherapy Response
por: Wu, Zhenghao, et al.
Publicado: (2022)

The scaffold protein Ajuba suppresses CdGAP activity in epithelia to maintain stable cell-cell contacts
por: McCormack, J. J., et al.
Publicado: (2017)

CD4+CD25(high), CD8+CD28– cells and thyroid autoantibodies in breast cancer patients
por: Biylgi, Oğuz, et al.
Publicado: (2014)

The role of soluble CD40L in immunosuppression
por: Schlom, Jeffrey, et al.
Publicado: (2013)

CD28-independent Induction of T Helper Cells and Immunoglobulin Class Switches Requires Costimulation by the Heat-stable Antigen
por: Wu, Yan, et al.
Publicado: (1998)

Prognostic significance of peripheral CD8+CD28+ and CD8+CD28− T cells in advanced non-small cell lung cancer patients treated with chemo(radio)therapy
por: Liu, Chao, et al.
Publicado: (2019)

Multiples aberrant phenotypes in multiple myeloma patient expressing CD56(-), CD28(+),CD19(+)
por: Leite, Luiz Arthur Calheiros, et al.
Publicado: (2012)

CD80-CD28 signaling controls the progression of inflammatory colorectal carcinogenesis
por: Scarpa, Marco, et al.
Publicado: (2015)

The Story of CD4(+)CD28(−) T Cells Revisited: Solved or Still Ongoing?
por: Maly, Kathrin, et al.
Publicado: (2015)

CD28 Signaling Drives Notch Ligand Expression on CD4 T Cells
por: Mitra, Ankita, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_vipm9kisoumi4nr3m6ab6dtrok