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Glycyrrhizin Protects Mice Against Experimental Autoimmune Encephalomyelitis by Inhibiting High-Mobility Group Box 1 (HMGB1) Expression and Neuronal HMGB1 Release

The inflammatory mediator high-mobility group box 1 (HMGB1) plays a critical role in the pathogenesis of human multiple sclerosis (MS) and mouse experimental autoimmune encephalomyelitis (EAE). Glycyrrhizin (GL), a glycoconjugated triterpene extracted from licorice root, has the ability to inhibit t...

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Detalles Bibliográficos
Autores principales:	Sun, Yan, Chen, Huoying, Dai, Jiapei, Wan, Zhongjun, Xiong, Ping, Xu, Yong, Han, Zhengrong, Chai, Weitai, Gong, Feili, Zheng, Fang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6036111/ https://www.ncbi.nlm.nih.gov/pubmed/30013568 http://dx.doi.org/10.3389/fimmu.2018.01518

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