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Upregulation of Heme Oxygenase-1 Endues Immature Dendritic Cells With More Potent and Durable Immunoregulatory Properties and Promotes Engraftment in a Stringent Mouse Cardiac Allotransplant Model

Heme oxygenase-1 (HO-1) is critical for the ability of immature dendritic cells (imDCs) to suppress T-cell responses. Induction of high HO-1 expression may markedly improve the tolerogenic capacity of imDCs. Here, we generated bone marrow-derived DCs (BMDCs) from BALB/c mice with low doses of GM-CSF...

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Detalles Bibliográficos
Autores principales:	Zhao, Yue, Jia, Yu, Wang, Lu, Chen, Song, Huang, Xia, Xu, Bingyang, Zhao, Guangyuan, Xiang, Ying, Yang, Jun, Chen, Gang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6036127/ https://www.ncbi.nlm.nih.gov/pubmed/30013566 http://dx.doi.org/10.3389/fimmu.2018.01515

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