Detection and Investigation of Eagle Effect Resistance to Vancomycin in Clostridium difficile With an ATP-Bioluminescence Assay

Vancomycin was bactericidal against Clostridium difficile at eightfold the minimum inhibitory concentration (MIC) using a traditional minimum bactericidal concentration (MBC) assay. However, at higher concentrations up to 64 × MIC, vancomycin displayed a paradoxical “more-drug-kills-less” Eagle effe...

Descripción completa

Detalles Bibliográficos
Autores principales: Jarrad, Angie M., Blaskovich, Mark A. T., Prasetyoputri, Anggia, Karoli, Tomislav, Hansford, Karl A., Cooper, Matthew A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6036128/
https://www.ncbi.nlm.nih.gov/pubmed/30013531
http://dx.doi.org/10.3389/fmicb.2018.01420

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6036128/
https://www.ncbi.nlm.nih.gov/pubmed/30013531
http://dx.doi.org/10.3389/fmicb.2018.01420

Ejemplares similares