Cargando…

The Ebola-Glycoprotein Modulates the Function of Natural Killer Cells

The Ebola virus (EBOV) uses evasion mechanisms that directly interfere with host T-cell antiviral responses. By steric shielding of human leukocyte antigen class-1, the Ebola glycoprotein (GP) blocks interaction with T-cell receptors (TCRs), thus rendering T cells unable to attack virus-infected cel...

Descripción completa

Detalles Bibliográficos
Autores principales:	Edri, Avishay, Shemesh, Avishai, Iraqi, Muhammed, Matalon, Omri, Brusilovsky, Michael, Hadad, Uzi, Radinsky, Olga, Gershoni-Yahalom, Orly, Dye, John M., Mandelboim, Ofer, Barda-Saad, Mira, Lobel, Leslie, Porgador, Angel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6036185/ https://www.ncbi.nlm.nih.gov/pubmed/30013549 http://dx.doi.org/10.3389/fimmu.2018.01428

Ejemplares similares

Sudan ebolavirus long recovered survivors produce GP-specific Abs that are of the IgG1 subclass and preferentially bind FcγRI
por: Radinsky, Olga, et al.
Publicado: (2017)

Survival in acute myeloid leukemia is associated with NKp44 splice variants
por: Shemesh, Avishai, et al.
Publicado: (2016)

N-Glycans Mediate the Ebola Virus-GP1 Shielding of Ligands to Immune Receptors and Immune Evasion
por: Iraqi, Muhammed, et al.
Publicado: (2020)

Targeting Natural Killer Cell Reactivity by Employing Antibody to NKp46: Implications for Type 1 Diabetes
por: Yossef, Rami, et al.
Publicado: (2015)

Expression of NKp46 Splice Variants in Nasal Lavage Following Respiratory Viral Infection: Domain 1-Negative Isoforms Predominate and Manifest Higher Activity
por: Shemer-Avni, Yonat, et al.
Publicado: (2017)

Cbl ubiquitin ligases mediate the inhibition of natural killer cell activity
por: Matalon, Omri, et al.
Publicado: (2016)

Regulation of the Functions of Natural Cytotoxicity Receptors by Interactions with Diverse Ligands and Alterations in Splice Variant Expression
por: Pazina, Tatiana, et al.
Publicado: (2017)

A novel mechanism for cancer cells to evade immune attack by NK cells: The interaction between NKp44 and proliferating cell nuclear antigen
por: Rosental, Benyamin, et al.
Publicado: (2012)

NKp44 and NKp30 splice variant profiles in decidua and tumor tissues: a comparative viewpoint
por: Shemesh, Avishai, et al.
Publicado: (2016)

Molecular-scale spatio-chemical control of the activating-inhibitory signal integration in NK cells
por: Toledo, Esti, et al.
Publicado: (2021)

NKp44-Derived Peptide Binds Proliferating Cell Nuclear Antigen and Mediates Tumor Cell Death
por: Shemesh, Avishai, et al.
Publicado: (2018)

Multiple viral proteins and immune response pathways act to generate robust long-term immunity in Sudan virus survivors
por: Sobarzo, Ariel, et al.
Publicado: (2019)

Carbohydrate-Mediated Modulation of NK Cell Receptor Function: Structural and Functional Influences of Heparan Sulfate Moieties Expressed on NK Cell Surface
por: Brusilovsky, Michael, et al.
Publicado: (2014)

First Trimester Pregnancy Loss and the Expression of Alternatively Spliced NKp30 Isoforms in Maternal Blood and Placental Tissue
por: Shemesh, Avishai, et al.
Publicado: (2015)

NKp44-Derived Peptide Used in Combination Stimulates Antineoplastic Efficacy of Targeted Therapeutic Drugs
por: Iraqi, Muhammed, et al.
Publicado: (2022)

Blocking the PCNA/NKp44 Checkpoint to Stimulate NK Cell Responses to Multiple Myeloma
por: Iraqi, Muhammed, et al.
Publicado: (2022)

WIP Remodeling Actin behind the Scenes: How WIP Reshapes Immune and Other Functions
por: Noy, Elad, et al.
Publicado: (2012)

Functional Characterization of Hexacorallia Phagocytic Cells
por: Snyder, Grace A., et al.
Publicado: (2021)

The Natural Cytotoxicity Receptor 1 Contribution to Early Clearance of Streptococcus pneumoniae and to Natural Killer-Macrophage Cross Talk
por: Elhaik-Goldman, Shirin, et al.
Publicado: (2011)

Heat stress increases immune cell function in Hexacorallia
por: Eliachar, Shir, et al.
Publicado: (2022)

Dual fluorescent labelling of the human malaria parasite Plasmodium falciparum for the analysis of the ABC type transporter pfmdr2
por: Rosental, Benyamin, et al.
Publicado: (2012)

Using high titer West Nile intravenous immunoglobulin from selected Israeli donors for treatment of West Nile virus infection
por: Ben-Nathan, David, et al.
Publicado: (2009)

Fc-Independent Protection from SARS-CoV-2 Infection by Recombinant Human Monoclonal Antibodies
por: Noy-Porat, Tal, et al.
Publicado: (2021)

CD100 on NK Cells Enhance IFNγ Secretion and Killing of Target Cells Expressing CD72
por: Mizrahi, Sa'ar, et al.
Publicado: (2007)

Evolution of Cellular Immunity Effector Cells; Perspective on Cytotoxic and Phagocytic Cellular Lineages
por: Mandujano-Tinoco, Edna Ayerim, et al.
Publicado: (2021)

NKp46 Clusters at the Immune Synapse and Regulates NK Cell Polarization
por: Hadad, Uzi, et al.
Publicado: (2015)

Life-extended glycosylated IL-2 promotes Treg induction and suppression of autoimmunity
por: Ottolenghi, Aner, et al.
Publicado: (2021)

mAb14, a Monoclonal Antibody against Cell Surface PCNA: A Potential Tool for Sezary Syndrome Diagnosis and Targeted Immunotherapy
por: Knaneh, Jamal, et al.
Publicado: (2023)

Differential IL-12 signaling induces human natural killer cell activating receptor-mediated ligand-specific expansion
por: Shemesh, Avishai, et al.
Publicado: (2022)

Anti-RhD antibody therapy modulates human natural killer cell function
por: Elias, Shlomo, et al.
Publicado: (2020)

Nanocomposite coatings for the prevention of surface contamination by coronavirus
por: Toledo, Esti, et al.
Publicado: (2022)

Natural Killer Receptor 1 Dampens the Development of Allergic Eosinophilic Airway Inflammation
por: Elhaik Goldman, Shirin, et al.
Publicado: (2016)

A pathogenic variant in the uncharacterized RNF212B gene results in severe aneuploidy male infertility and repeated IVF failure
por: Gershoni, Moran, et al.
Publicado: (2023)

Harnessing Soluble NK Cell Killer Receptors for the Generation of Novel Cancer Immune Therapy
por: Arnon, Tal I., et al.
Publicado: (2008)

Molecular and cellular correlates in Kv channel clustering: entropy-based regulation of cluster ion channel density
por: Lewin, Limor, et al.
Publicado: (2020)

Multifunctional Nanoscale Platform for the Study of T Cell Receptor Segregation
por: Toledo, Esti, et al.
Publicado: (2023)

Controlled Shape and Porosity of Polymeric Colloids by Photo-Induced Phase Separation
por: Hadad, Elad, et al.
Publicado: (2019)

Correction: Harnessing Soluble NK Cell Killer Receptors for the Generation of Novel Cancer Immune Therapy
por: Arnon, Tal I., et al.
Publicado: (2008)

Correction: Harnessing Soluble NK Cell Killer Receptors for the Generation of Novel Cancer Immune Therapy
por: Arnon, Tal I., et al.
Publicado: (2015)

Ebola, the killer virus
por: Ghazanfar, Haider, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_o2njnfrnkdbulqs8gb9qv51nvk