miR-21 Protects Against Ischemia/Reperfusion-Induced Acute Kidney Injury by Preventing Epithelial Cell Apoptosis and Inhibiting Dendritic Cell Maturation

Renal tubular injury and innate immune responses induced by hypoxia contribute to acute kidney injury. Accumulating evidence suggests that miR-21 overexpression protects against kidney ischemia injury. Additionally, miR-21 emerges as a key inhibitor in dendritic cell maturation. Thus, we hypothesize...

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Detalles Bibliográficos
Autores principales: Song, Nana, Zhang, Ting, Xu, XiaLian, Lu, Zhihui, Yu, Xiaofang, Fang, Yi, Hu, Jiachang, Jia, Ping, Teng, Jie, Ding, Xiaoqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6036242/
https://www.ncbi.nlm.nih.gov/pubmed/30013485
http://dx.doi.org/10.3389/fphys.2018.00790

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