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A Mouse Model of Creatine Transporter Deficiency Reveals Impaired Motor Function and Muscle Energy Metabolism

Creatine serves as fast energy buffer in organs of high-energy demand such as brain and skeletal muscle. L-Arginine:glycine amidinotransferase (AGAT) and guanidinoacetate N-methyltransferase are responsible for endogenous creatine synthesis. Subsequent uptake into target organs like skeletal muscle,...

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Detalles Bibliográficos
Autores principales:	Stockebrand, Malte, Sasani, Ali, Das, Devashish, Hornig, Sönke, Hermans-Borgmeyer, Irm, Lake, Hannah A., Isbrandt, Dirk, Lygate, Craig A., Heerschap, Arend, Neu, Axel, Choe, Chi-Un
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6036259/ https://www.ncbi.nlm.nih.gov/pubmed/30013483 http://dx.doi.org/10.3389/fphys.2018.00773

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