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The IGF2/IGF1R/Nanog Signaling Pathway Regulates the Proliferation of Acute Myeloid Leukemia Stem Cells

Acute myeloid leukemia is an aggressive disease characterized by clonal proliferation and differentiation into immature hematopoietic cells of dysfunctional myeloid precursors. Accumulating evidence shows that CD34(+)CD38(-) leukemia stem cells (LSCs) are responsible for drug resistance, metastasis,...

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Detalles Bibliográficos
Autores principales: Xu, Dan-dan, Wang, Ying, Zhou, Peng-jun, Qin, Shu-rong, Zhang, Rong, Zhang, Yi, Xue, Xue, Wang, Jianping, Wang, Xia, Chen, Hong-ce, Wang, Xiao, Pan, Yu-wei, Zhang, Li, Yan, Hai-zhao, Liu, Qiu-ying, Liu, Zhong, Chen, Su-hong, Chen, Hong-yuan, Wang, Yi-fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6036281/
https://www.ncbi.nlm.nih.gov/pubmed/30013477
http://dx.doi.org/10.3389/fphar.2018.00687

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