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Analysis of correlation between estradiol and fracture of femur neck

Osteoporosis is a major public health challenge all over the world. Estrogen hormone was cited amongst other hormones to be an efficient hormone for the production and maintenance of bone density. This study was designed with the purpose of evaluating and analyzing the estradiol effect on fractures...

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Autores principales: Sharifi, Mohammad Davood, Mohebbi, Masoud, Farrokhfar, Mahmood, Farzaneh, Roohie, Disfani, Hamideh Feiz, Hashemian, Amir Masoud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PAGEPress Publications, Pavia, Italy 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6036315/
https://www.ncbi.nlm.nih.gov/pubmed/29991984
http://dx.doi.org/10.4081/ejtm.2018.7379
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author Sharifi, Mohammad Davood
Mohebbi, Masoud
Farrokhfar, Mahmood
Farzaneh, Roohie
Disfani, Hamideh Feiz
Hashemian, Amir Masoud
author_facet Sharifi, Mohammad Davood
Mohebbi, Masoud
Farrokhfar, Mahmood
Farzaneh, Roohie
Disfani, Hamideh Feiz
Hashemian, Amir Masoud
author_sort Sharifi, Mohammad Davood
collection PubMed
description Osteoporosis is a major public health challenge all over the world. Estrogen hormone was cited amongst other hormones to be an efficient hormone for the production and maintenance of bone density. This study was designed with the purpose of evaluating and analyzing the estradiol effect on fractures of femur neck in the Iranian society. This study evaluated men over 50 years of age suffering with mild trauma (falling off the same level height or lower) and with a fracture on their femur neck. Also, their serum level of estradiol was measured with an ELISA method. Using this procedure, the patients were assigned into groups with either normal estradiol serum level (10pg/ml and higher) or with lower than normal level (lower than 10 pg/ml). A control group including 50-year-old and older men without hip fracture, or its history, was chosen to access their estradiol serum level. Data collected from these two groups were statistically compared. A total of 120 patients were evaluated (60 in the control and 60 in the test group). The mean age of patients in the control and test groups were 67.9±10.22 and 69.5±8.84 years, respectively (p=0.376). Smoker patients’ percentages in the control and test groups were 35% and 31.7%, respectively (p=0.699). On the basis of the serum estradiol level, patients’ percentages with low estradiol level in control and test groups were 10% and 16.7%, respectively (p=0.283). The only significant factor in predicting serum estradiol level was smoking. In conclusion, in this study it was observed that fractures of the femoral neck following a mild trauma were not correlated to low level of serum estradiol.
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spelling pubmed-60363152018-07-10 Analysis of correlation between estradiol and fracture of femur neck Sharifi, Mohammad Davood Mohebbi, Masoud Farrokhfar, Mahmood Farzaneh, Roohie Disfani, Hamideh Feiz Hashemian, Amir Masoud Eur J Transl Myol Article Osteoporosis is a major public health challenge all over the world. Estrogen hormone was cited amongst other hormones to be an efficient hormone for the production and maintenance of bone density. This study was designed with the purpose of evaluating and analyzing the estradiol effect on fractures of femur neck in the Iranian society. This study evaluated men over 50 years of age suffering with mild trauma (falling off the same level height or lower) and with a fracture on their femur neck. Also, their serum level of estradiol was measured with an ELISA method. Using this procedure, the patients were assigned into groups with either normal estradiol serum level (10pg/ml and higher) or with lower than normal level (lower than 10 pg/ml). A control group including 50-year-old and older men without hip fracture, or its history, was chosen to access their estradiol serum level. Data collected from these two groups were statistically compared. A total of 120 patients were evaluated (60 in the control and 60 in the test group). The mean age of patients in the control and test groups were 67.9±10.22 and 69.5±8.84 years, respectively (p=0.376). Smoker patients’ percentages in the control and test groups were 35% and 31.7%, respectively (p=0.699). On the basis of the serum estradiol level, patients’ percentages with low estradiol level in control and test groups were 10% and 16.7%, respectively (p=0.283). The only significant factor in predicting serum estradiol level was smoking. In conclusion, in this study it was observed that fractures of the femoral neck following a mild trauma were not correlated to low level of serum estradiol. PAGEPress Publications, Pavia, Italy 2018-05-16 /pmc/articles/PMC6036315/ /pubmed/29991984 http://dx.doi.org/10.4081/ejtm.2018.7379 Text en http://creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution Noncommercial License (by-nc 4.0) which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited.
spellingShingle Article
Sharifi, Mohammad Davood
Mohebbi, Masoud
Farrokhfar, Mahmood
Farzaneh, Roohie
Disfani, Hamideh Feiz
Hashemian, Amir Masoud
Analysis of correlation between estradiol and fracture of femur neck
title Analysis of correlation between estradiol and fracture of femur neck
title_full Analysis of correlation between estradiol and fracture of femur neck
title_fullStr Analysis of correlation between estradiol and fracture of femur neck
title_full_unstemmed Analysis of correlation between estradiol and fracture of femur neck
title_short Analysis of correlation between estradiol and fracture of femur neck
title_sort analysis of correlation between estradiol and fracture of femur neck
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6036315/
https://www.ncbi.nlm.nih.gov/pubmed/29991984
http://dx.doi.org/10.4081/ejtm.2018.7379
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