Knockout of SIRT4 decreases chemosensitivity to 5-FU in colorectal cancer cells

Previous studies demonstrated that sirtuin (SIRT) 4 is aberrantly expressed in human malignant tumors and is associated with poor prognosis in patients with colorectal cancer. However, the role of SIRT4 in the progression of human colorectal cancer (CRC) and in chemotherapy remains unclear. In the p...

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Detalles Bibliográficos
Autores principales: Zhu, Yuanyuan, Wang, Guangyu, Li, Xiaobo, Wang, Tianzhen, Weng, Mingjiao, Zhang, Yanqiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6036483/
https://www.ncbi.nlm.nih.gov/pubmed/30008852
http://dx.doi.org/10.3892/ol.2018.8850

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6036483/
https://www.ncbi.nlm.nih.gov/pubmed/30008852
http://dx.doi.org/10.3892/ol.2018.8850

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