Cargando…

Knockout of SIRT4 decreases chemosensitivity to 5-FU in colorectal cancer cells

Previous studies demonstrated that sirtuin (SIRT) 4 is aberrantly expressed in human malignant tumors and is associated with poor prognosis in patients with colorectal cancer. However, the role of SIRT4 in the progression of human colorectal cancer (CRC) and in chemotherapy remains unclear. In the p...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhu, Yuanyuan, Wang, Guangyu, Li, Xiaobo, Wang, Tianzhen, Weng, Mingjiao, Zhang, Yanqiao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2018
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6036483/ https://www.ncbi.nlm.nih.gov/pubmed/30008852 http://dx.doi.org/10.3892/ol.2018.8850

Ejemplares similares

Up-regulation of FAT4 enhances the chemosensitivity of colorectal cancer cells treated by 5-FU
por: Li, Qianyuan, et al.
Publicado: (2020)

miR-211 facilitates platinum chemosensitivity by blocking the DNA damage response (DDR) in ovarian cancer
por: Wang, Tianzhen, et al.
Publicado: (2019)

Resveratrol Chemosensitizes TNF-β-Induced Survival of 5-FU-Treated Colorectal Cancer Cells
por: Buhrmann, Constanze, et al.
Publicado: (2018)

Visfatin inhibits colon cancer cell apoptosis and decreases chemosensitivity to 5-FU by promoting the SDF-1/CXCR4/Akt axis
por: Zhao, Quan, et al.
Publicado: (2022)

Proteomic analysis of the chemosensitizing effect of curcumin on CRC cells treated with 5-FU
por: Yang, Jingbo, et al.
Publicado: (2022)

ZFP36 Binds With PRC1 to Inhibit Tumor Growth and Increase 5-Fu Chemosensitivity of Hepatocellular Carcinoma
por: Chen, Weiqian, et al.
Publicado: (2020)

Identification of TMEM208 and PQLC2 as reference genes for normalizing mRNA expression in colorectal cancer treated with aspirin
por: Zhu, Yuanyuan, et al.
Publicado: (2017)

Knockdown of BAP31 Downregulates Galectin-3 to Inhibit the Wnt/β-Catenin Signaling Pathway to Modulate 5-FU Chemosensitivity and Cancer Stemness in Colorectal Cancer
por: Liu, Jingjing, et al.
Publicado: (2023)

Inhibition of protein FAK enhances 5-FU chemosensitivity to gastric carcinoma via p53 signaling pathways
por: Hou, Jingjing, et al.
Publicado: (2019)

USP22 knockdown enhanced chemosensitivity of hepatocellular carcinoma cells to 5-Fu by up-regulation of Smad4 and suppression of Akt
por: Zhang, Jing, et al.
Publicado: (2017)

Long non-coding RNA H19 confers 5-Fu resistance in colorectal cancer by promoting SIRT1-mediated autophagy
por: Wang, Meng, et al.
Publicado: (2018)

All-Trans Retinoic Acid Enhances Chemosensitivity to 5-FU by Targeting miR-378c/E2F7 Axis in Colorectal Cancer
por: Li, Ji, et al.
Publicado: (2021)

Inhibition of CDK1 Reverses the Resistance of 5-Fu in Colorectal Cancer
por: Zhu, Yiping, et al.
Publicado: (2020)

Chemosensitization of HT29 and HT29-5FU Cell Lines by a Combination of a Multi-Tyrosine Kinase Inhibitor and 5FU Downregulates ABCC1 and Inhibits PIK3CA in Light of Their Importance in Saudi Colorectal Cancer
por: Abdalla, Ashraf N., et al.
Publicado: (2021)

Aspirin suppresses chemoresistance and enhances antitumor activity of 5-Fu in 5-Fu-resistant colorectal cancer by abolishing 5-Fu-induced NF-κB activation
por: Fu, Jinbo, et al.
Publicado: (2019)

The deacetylation of Foxk2 by Sirt1 reduces chemosensitivity to cisplatin
por: Wang, Xi‐wen, et al.
Publicado: (2021)

Managing 5FU Cardiotoxicity in Colorectal Cancer Treatment
por: Anaka, Matthew, et al.
Publicado: (2022)

Targeting Thymidylate Synthase Enhances the Chemosensitivity of Triple-Negative Breast Cancer Towards 5-FU-Based Combinatorial Therapy
por: Haritha, Nair Hariprasad, et al.
Publicado: (2021)

Genome-wide CRISPR Screening Reveals Pyrimidine Metabolic Reprogramming in 5-FU Chronochemotherapy of Colorectal Cancer
por: Niu, Ya, et al.
Publicado: (2022)

AURKA Increase the Chemosensitivity of Colon Cancer Cells to Oxaliplatin by Inhibiting the TP53-Mediated DNA Damage Response Genes
por: Shan, Baocong, et al.
Publicado: (2020)

Inhibition of circular RNA CDR1as increases chemosensitivity of 5‐FU‐resistant BC cells through up‐regulating miR‐7
por: Yang, Wei, et al.
Publicado: (2019)

Loss of ABCB4 attenuates the caspase-dependent apoptosis regulating resistance to 5-Fu in colorectal cancer
por: Hu, Hanqing, et al.
Publicado: (2018)

The role of GLI1 for 5-Fu resistance in colorectal cancer
por: Zhang, Lining, et al.
Publicado: (2017)

5-FU Metabolism in Cancer and Orally-Administrable 5-FU Drugs
por: Miura, Koh, et al.
Publicado: (2010)

Proton pump inhibitors increase the chemosensitivity of patients with advanced colorectal cancer
por: Wang, Xiaoyu, et al.
Publicado: (2017)

Halofuginone inhibits tumorigenic progression of 5-FU-resistant human colorectal cancer HCT-15/FU cells by targeting miR-132-3p in vitro
por: Wang, Chen, et al.
Publicado: (2020)

A polymorphism in ABCC4 is related to efficacy of 5-FU/capecitabine-based chemotherapy in colorectal cancer patients
por: Chen, Qi, et al.
Publicado: (2017)

5-FU-hydrogel inhibits colorectal peritoneal carcinomatosis and tumor growth in mice
por: Wang, Yongsheng, et al.
Publicado: (2010)

Wnt pathway is involved in 5-FU drug resistance of colorectal cancer cells
por: He, Lingfeng, et al.
Publicado: (2018)

KLF4 targets RAB26 and decreases 5-FU resistance through inhibiting autophagy in colon cancer
por: Zheng, Yu, et al.
Publicado: (2023)

Mechanism of acquired 5FU resistance and strategy for overcoming 5FU resistance focusing on 5FU metabolism in colon cancer cell lines
por: Suetsugu, Tomonari, et al.
Publicado: (2021)

CISD2 enhances the chemosensitivity of gastric cancer through the enhancement of 5‐FU‐induced apoptosis and the inhibition of autophagy by AKT/mTOR pathway
por: Sun, Yi, et al.
Publicado: (2017)

METTL3 antagonizes 5-FU chemotherapy and confers drug resistance in colorectal carcinoma
por: Li, Min, et al.
Publicado: (2022)

METTL3 antagonizes 5-FU chemotherapy and confers drug resistance in colorectal carcinoma
por: Li, Min, et al.
Publicado: (2023)

Pharmacokinetics and pharmacodynamics of locoregional 5 fluorouracil (5FU) in advanced colorectal liver metastases.
por: Goldberg, J. A., et al.
Publicado: (1988)

Determining the optimal 5-FU therapeutic dosage in the treatment of colorectal cancer patients
por: Fang, Ling, et al.
Publicado: (2016)

Combinational inhibition of EGFR and YAP reverses 5-Fu resistance in colorectal cancer
por: Huang, Changhao, et al.
Publicado: (2020)

Overexpression of sortilin is associated with 5‐FU resistance and poor prognosis in colorectal cancer
por: Blondy, Sabrina, et al.
Publicado: (2020)

Synthesis and Chemopreventive Potential of 5-FU/Genistein Hybrids on Colorectal Cancer Cells
por: Moreno-Quintero, Gustavo, et al.
Publicado: (2022)

Twelve weeks of protracted venous infusion of fluorouracil (5-FU) is as effective as 6 months of bolus 5-FU and folinic acid as adjuvant treatment in colorectal cancer
por: Saini, A, et al.
Publicado: (2003)

Cannot write session to /tmp/vufind_sessions/sess_0suuer5re881r7mvp0ehpeue5e