Systemic Fibrinolytic Therapy in the Presence of Absolute Contraindication; a Case Series
In massive pulmonary embolism (PE), fibrinolytic therapy is a potential lifesaving treatment; therefore, if other treatments are not available, the physicians encounter this question: can we accept the risk of complications from fibrinolytic therapy, especially intracranial hemorrhage, in the presen...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Shahid Beheshti University of Medical Sciences
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6036529/ https://www.ncbi.nlm.nih.gov/pubmed/30009227 |
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author | Pishgahi, Mahdi Alirezaei, Toktam Hajimoradi, Behzad Nekooghadam, S. Mojtaba Shahi, Shima |
author_facet | Pishgahi, Mahdi Alirezaei, Toktam Hajimoradi, Behzad Nekooghadam, S. Mojtaba Shahi, Shima |
author_sort | Pishgahi, Mahdi |
collection | PubMed |
description | In massive pulmonary embolism (PE), fibrinolytic therapy is a potential lifesaving treatment; therefore, if other treatments are not available, the physicians encounter this question: can we accept the risk of complications from fibrinolytic therapy, especially intracranial hemorrhage, in the presence of absolute contraindication, in order to save the patient’s life? Here, we describe three cases of massive PE with absolute contraindication for fibrinolytic therapy who presented to emergency department following dyspnea. Since, surgical or catheter embolectomy were not available and patients were very high risk for transferring to another hospital, systemic fibrinolytic was administered. The patients improved clinically and were discharged from hospital. It seems that, if no other acceptable treatments are available, physicians could consider fibrinolytic therapy, even at the presence of contraindication, to save the patient’s life. |
format | Online Article Text |
id | pubmed-6036529 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Shahid Beheshti University of Medical Sciences |
record_format | MEDLINE/PubMed |
spelling | pubmed-60365292018-07-13 Systemic Fibrinolytic Therapy in the Presence of Absolute Contraindication; a Case Series Pishgahi, Mahdi Alirezaei, Toktam Hajimoradi, Behzad Nekooghadam, S. Mojtaba Shahi, Shima Emerg (Tehran) Case Report In massive pulmonary embolism (PE), fibrinolytic therapy is a potential lifesaving treatment; therefore, if other treatments are not available, the physicians encounter this question: can we accept the risk of complications from fibrinolytic therapy, especially intracranial hemorrhage, in the presence of absolute contraindication, in order to save the patient’s life? Here, we describe three cases of massive PE with absolute contraindication for fibrinolytic therapy who presented to emergency department following dyspnea. Since, surgical or catheter embolectomy were not available and patients were very high risk for transferring to another hospital, systemic fibrinolytic was administered. The patients improved clinically and were discharged from hospital. It seems that, if no other acceptable treatments are available, physicians could consider fibrinolytic therapy, even at the presence of contraindication, to save the patient’s life. Shahid Beheshti University of Medical Sciences 2018 2018-04-22 /pmc/articles/PMC6036529/ /pubmed/30009227 Text en Copyright (2018) Shahid Beheshti University ofMedical Sciences This open-access article distributed under the terms of the Creative Commons Attribution NonCommercial 3.0 License (CC BY-NC 3.0)(https://creativecommons.org/licenses/by-nc/3.0/). |
spellingShingle | Case Report Pishgahi, Mahdi Alirezaei, Toktam Hajimoradi, Behzad Nekooghadam, S. Mojtaba Shahi, Shima Systemic Fibrinolytic Therapy in the Presence of Absolute Contraindication; a Case Series |
title | Systemic Fibrinolytic Therapy in the Presence of Absolute Contraindication; a Case Series |
title_full | Systemic Fibrinolytic Therapy in the Presence of Absolute Contraindication; a Case Series |
title_fullStr | Systemic Fibrinolytic Therapy in the Presence of Absolute Contraindication; a Case Series |
title_full_unstemmed | Systemic Fibrinolytic Therapy in the Presence of Absolute Contraindication; a Case Series |
title_short | Systemic Fibrinolytic Therapy in the Presence of Absolute Contraindication; a Case Series |
title_sort | systemic fibrinolytic therapy in the presence of absolute contraindication; a case series |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6036529/ https://www.ncbi.nlm.nih.gov/pubmed/30009227 |
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