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Inhibition of RAGE Attenuates Cigarette Smoke-Induced Lung Epithelial Cell Damage via RAGE-Mediated Nrf2/DAMP Signaling

The oxidative stress and cellular apoptosis by environmental factor including cigarette smoke induces alveolar airway remodeling leading to chronic obstructive pulmonary disease (COPD). Recently, the receptor for advanced glycan end products (RAGE) which is highly expressed in alveolar epithelium is...

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Detalles Bibliográficos
Autores principales: Lee, Hanbyeol, Lee, Jooyeon, Hong, Seok-Ho, Rahman, Irfan, Yang, Se-Ran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6036614/
https://www.ncbi.nlm.nih.gov/pubmed/30013476
http://dx.doi.org/10.3389/fphar.2018.00684