Cargando…

Antileishmanial and Immunomodulatory Effect of Babassu-Loaded PLGA Microparticles: A Useful Drug Target to Leishmania amazonensis Infection

The immunological and the anti-Leishmania amazonensis activity of babassu-loaded poly(lactic-co-glycolic acid) [PLGA] microparticles was evaluated. The anti-Leishmania activity was evaluated against promastigotes or amastigotes forms, in Balb/c macrophages. The size of the microparticles ranged from...

Descripción completa

Detalles Bibliográficos
Autores principales:	da Silva, Mayara Cristina Pinto, Brito, Jefferson Mesquita, Ferreira, Amalia dos Santos, Vale, Andre Alvares Marques, dos Santos, Ana Paula Azevedo, Silva, Lucilene Amorim, Pereira, Paulo Vitor Soeiro, Nascimento, Flavia Raquel Fernandes, Nicolete, Roberto, Guerra, Rosane Nassar Meireles
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6036798/ https://www.ncbi.nlm.nih.gov/pubmed/30046335 http://dx.doi.org/10.1155/2018/3161045

Ejemplares similares

Immunomodulatory and Antimicrobial Activity of Babassu Mesocarp Improves the Survival in Lethal Sepsis
por: Barroqueiro, Elizabeth S. B., et al.
Publicado: (2016)

Antileishmanial activity of Melampodium divaricatum and Casearia sylvestris essential oils on Leishmania amazonensis
por: Moreira, Raquel Regina Duarte, et al.
Publicado: (2019)

Antileishmanial Activity of 4,8-Dimethoxynaphthalenyl Chalcones on Leishmania amazonensis
por: de Santiago-Silva, Kaio Maciel, et al.
Publicado: (2022)

Brazilian Propolis Antileishmanial and Immunomodulatory Effects
por: da Silva, Suelen Santos, et al.
Publicado: (2013)

Evaluation of Antileishmanial Activity of Albaha Medicinal Plants against Leishmania amazonensis
por: Al-Sokari, Saeed S., et al.
Publicado: (2015)

Biflavones from Platonia insignis Mart. Flowers Promote In Vitro Antileishmanial and Immunomodulatory Effects against Internalized Amastigote Forms of Leishmania amazonensis
por: Bezerra, Érika Alves, et al.
Publicado: (2021)

Leishmania amazonensis from distinct clinical forms/hosts has polymorphisms in Lipophosphoglycans, displays variations in immunomodulatory properties and, susceptibility to antileishmanial drugs
por: Rêgo, Felipe D., et al.
Publicado: (2022)

Anti-Inflammatory Activity of Babassu Oil and Development of a Microemulsion System for Topical Delivery
por: Reis, Mysrayn Y. F. A., et al.
Publicado: (2017)

Synergistic Antileishmanial Effect of Oregano Essential Oil and Silver Nanoparticles: Mechanisms of Action on Leishmania amazonensis
por: Alves, Alex Barbosa, et al.
Publicado: (2023)

Antileishmanial effects of γCdcPLI, a phospholipase A(2) inhibitor from Crotalus durissus collilineatus snake serum, on Leishmania (Leishmania) amazonensis
por: Gonçalves, Marina Neves, et al.
Publicado: (2023)

In Vitro and In Vivo Wound Healing and Anti-Inflammatory Activities of Babassu Oil (Attalea speciosa Mart. Ex Spreng., Arecaceae)
por: Santos, José Alex A., et al.
Publicado: (2020)

Imidazo[1,2-a]pyrimidine as a New Antileishmanial Pharmacophore against Leishmania amazonensis Promastigotes and Amastigotes
por: Kumar, Ravinder, et al.
Publicado: (2023)

Antileishmanial Activity of Amphotericin B-loaded-PLGA Nanoparticles: An Overview
por: Palma, Ernesto, et al.
Publicado: (2018)

Essential oils: in vitro activity against Leishmania amazonensis, cytotoxicity and chemical composition
por: Andrade, Milene Aparecida, et al.
Publicado: (2016)

Second-generation pterocarpanquinones: synthesis and antileishmanial activity
por: Faiões, Viviane dos Santos, et al.
Publicado: (2018)

Babassu nut residues: potential for bioenergy use in the North and Northeast of Brazil
por: de Paula Protásio, Thiago, et al.
Publicado: (2014)

Comparing the Antileishmanial Activity of Gold(I) and Gold(III) Compounds in L. amazonensis and L. braziliensis in Vitro
por: Minori, Karen, et al.
Publicado: (2020)

1,4-Disubstituted-1,2,3-Triazole Compounds Induce Ultrastructural Alterations in Leishmania amazonensis Promastigote: An in Vitro Antileishmanial and in Silico Pharmacokinetic Study
por: Almeida-Souza, Fernando, et al.
Publicado: (2020)

Benzylamines as highly potent inhibitors of the sterol biosynthesis pathway in Leishmania amazonensis leading to oxidative stress and ultrastructural alterations
por: de Macedo-Silva, Sara Teixeira, et al.
Publicado: (2022)

Ethanolic Extract of the Fungus Trichoderma asperelloides Induces Ultrastructural Effects and Death on Leishmania amazonensis
por: Lopes, Danielle de Sousa, et al.
Publicado: (2020)

Virtual Screening and the In Vitro Assessment of the Antileishmanial Activity of Lignans
por: dos Santos Maia, Mayara, et al.
Publicado: (2020)

Brazilian Green Propolis: Anti-Inflammatory Property by an Immunomodulatory Activity
por: Machado, Joleen Lopes, et al.
Publicado: (2012)

Association of PLGA Microspheres to Carrier Pellets by Fluid Bed Coating: A Novel Approach towards Improving the Flowability of Microparticles
por: Beringhs, André O'Reilly, et al.
Publicado: (2018)

Carapa guianensis Aublet (Andiroba) Seed Oil: Chemical Composition and Antileishmanial Activity of Limonoid-Rich Fractions
por: Oliveira, Iara dos Santos da Silva, et al.
Publicado: (2018)

ACW-02 an Acridine Triazolidine Derivative Presents Antileishmanial Activity Mediated by DNA Interaction and Immunomodulation
por: Albino, Sonaly Lima, et al.
Publicado: (2023)

Impact of Extraction Parameters on the Recovery of Lipolytic Activity from Fermented Babassu Cake
por: Silva, Jaqueline N., et al.
Publicado: (2014)

Endlicheria bracteolata (Meisn.) Essential Oil as a Weapon Against Leishmania amazonensis: In Vitro Assay
por: Rottini, Mariana Margatto, et al.
Publicado: (2019)

Cinnamides Target Leishmania amazonensis Arginase Selectively
por: da Silva, Edson Roberto, et al.
Publicado: (2020)

The Influence of Anthocyanidin Profile on Antileishmanial Activity of Arrabidaea chica Morphotypes
por: Moragas-Tellis, Carla Junqueira, et al.
Publicado: (2020)

Intake, Nutrient Apparent Digestibility, and Ruminal Constituents of Crossbred Dorper × Santa Inês Sheep Fed Diets with Babassu Mesocarp Flour
por: Gerude Neto, Osman José de Aguiar, et al.
Publicado: (2016)

Antileishmanial activity and immunomodulatory effect of secosubamolide, a butanolide isolated from Nectandra oppositifolia (Lauraceae)
por: da Costa-Silva, Thais A., et al.
Publicado: (2019)

Economic Analysis of the Production of Amylases and Other Hydrolases by Aspergillus awamori in Solid-State Fermentation of Babassu Cake
por: de Castro, Aline Machado, et al.
Publicado: (2010)

Antileishmanial activity of diterpene acids in copaiba oil
por: dos Santos, Adriana Oliveira, et al.
Publicado: (2013)

Immunomodulatory Effects of Cinnamaldehyde in Staphylococcus aureus-Infected Wounds
por: Figueiredo, Cristiane Santos Silva e Silva, et al.
Publicado: (2023)

Anticancer efficacy of perillyl alcohol-bearing PLGA microparticles
por: Farazuddin, Mohammad, et al.
Publicado: (2012)

Preclinical Development and In Vivo Efficacy of Ceftiofur-PLGA Microparticles
por: Vilos, Cristian, et al.
Publicado: (2015)

Babassu aqueous extract (BAE) as an adjuvant for T helper (Th)1-dependent immune responses in mice of a Th2 immune response-prone strain
por: Guerra, Rosane NM, et al.
Publicado: (2011)

Endoplasmic Stress Affects the Coinfection of Leishmania Amazonensis and the Phlebovirus (Bunyaviridae) Icoaraci
por: dos Santos, José V., et al.
Publicado: (2022)

Evaluation of Antileishmanial Activity of Selected Brazilian Plants and Identification of the Active Principles
por: Filho, Valdir Cechinel, et al.
Publicado: (2013)

Cytotoxic and Antileishmanial Effects of the Monoterpene β-Ocimene
por: de Sousa, Julyanne Maria Saraiva, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_vub2bqk7tsr01ppje2k85al3cs