Cargando…

Andrographolide Ameliorates Diabetic Cardiomyopathy in Mice by Blockage of Oxidative Damage and NF-κB-Mediated Inflammation

Andrographolide (Andro), a major bioactive component obtained from Andrographis paniculata Nees, has exerted wide antioxidant as well as cytoprotective properties. However, whether Andro treatment could retard the progress of diabetic cardiomyopathy (DCM) remains unknown. In this study, we evaluated...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liang, Ershun, Liu, Xue, Du, Zhanhui, Yang, Ruixue, Zhao, Yuxia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6036810/ https://www.ncbi.nlm.nih.gov/pubmed/30046380 http://dx.doi.org/10.1155/2018/9086747

Ejemplares similares

Andrographolide sulfonate ameliorates lipopolysaccharide-induced acute lung injury in mice by down-regulating MAPK and NF-κB pathways
por: Peng, Shuang, et al.
Publicado: (2016)

Andrographolide Ameliorates Liver Fibrosis in Mice: Involvement of TLR4/NF-κB and TGF-β1/Smad2 Signaling Pathways
por: Lin, Liteng, et al.
Publicado: (2018)

Andrographolide ameliorates OVA-induced lung injury in mice by suppressing ROS-mediated NF-κB signaling and NLRP3 inflammasome activation
por: Peng, Shuang, et al.
Publicado: (2016)

Effects of andrographolide on postoperative cognitive dysfunction and the association with NF-κB/MAPK pathway
por: Ding, Yongbo, et al.
Publicado: (2017)

Attenuation of Innate Immunity by Andrographolide Derivatives Through NF-κB Signaling Pathway
por: Nie, Xin, et al.
Publicado: (2017)

Andrographolide Derivative AL-1 Ameliorates Dextran Sodium Sulfate-Induced Murine Colitis by Inhibiting NF-κB and MAPK Signaling Pathways
por: Jing, Mei, et al.
Publicado: (2019)

Andrographolide sulfate inhibited NF-κB activation and alleviated pneumonia induced by poly I:C in mice
por: Cui, Jian, et al.
Publicado: (2020)

Andrographolide Protects against LPS-Induced Acute Lung Injury by Inactivation of NF-κB
por: Zhu, Tao, et al.
Publicado: (2013)

Andrographolide Suppresses Proliferation of Nasopharyngeal Carcinoma Cells via Attenuating NF-κB Pathway
por: Peng, Tao, et al.
Publicado: (2015)

Andrographolide Ameliorates Inflammation and Fibrogenesis and Attenuates Inflammasome Activation in Experimental Non-Alcoholic Steatohepatitis
por: Cabrera, Daniel, et al.
Publicado: (2017)

Andrographolide
por: Yan, Yu, et al.
Publicado: (2018)

Neferine inhibits proliferation and collagen synthesis induced by high glucose in cardiac fibroblasts and reduces cardiac fibrosis in diabetic mice
por: Liu, Xue, et al.
Publicado: (2016)

Correction: Neferine inhibits proliferation and collagen synthesis induced by high glucose in cardiac fibroblasts and reduces cardiac fibrosis in diabetic mice
por: Liu, Xue, et al.
Publicado: (2022)

Andrographolide Suppress Tumor Growth by Inhibiting TLR4/NF-κB Signaling Activation in Insulinoma
por: Zhang, Qian-Qian, et al.
Publicado: (2014)

Topical Ascorbic Acid Ameliorates Oxidative Stress-Induced Corneal Endothelial Damage via Suppression of Apoptosis and Autophagic Flux Blockage
por: Hsueh, Yi-Jen, et al.
Publicado: (2020)

Andrographolide inhibits the activation of NF-κB and MMP-9 activity in H3255 lung cancer cells
por: LUO, WEIMIN, et al.
Publicado: (2013)

Multi-Targeting Andrographolide, a Novel NF-κB Inhibitor, as a Potential Therapeutic Agent for Stroke
por: Yang, Chih-Hao, et al.
Publicado: (2017)

Andrographolide Suppress Tumor Growth by Inhibiting TLR4/NF-κB Signaling Activation in Insulinoma: Erratum
por: Zhang, Qian-Qian, et al.
Publicado: (2020)

Retraction: Andrographolide Suppress Tumor Growth by Inhibiting TLR4/NF-κB Signaling Activation in Insulinoma
Publicado: (2021)

Angiotensin-(1–7) ameliorates sepsis-induced cardiomyopathy by alleviating inflammatory response and mitochondrial damage through the NF-κB and MAPK pathways
por: Chen, Xin-Sen, et al.
Publicado: (2023)

Andrographolide derivative AL-1 ameliorates TNBS-induced colitis in mice: involvement of NF-кB and PPAR-γ signaling pathways
por: Yang, Yali, et al.
Publicado: (2016)

Glabridin Ameliorates Alcohol-Caused Liver Damage by Reducing Oxidative Stress and Inflammation via p38 MAPK/Nrf2/NF-κB Pathway
por: Wang, Mengyao, et al.
Publicado: (2023)

CDK7 inhibition suppresses rheumatoid arthritis inflammation via blockage of NF‐κB activation and IL‐1β/IL‐6 secretion
por: Hong, Honghai, et al.
Publicado: (2017)

Andrographolide induces DNA damage in prostate cancer cells
por: Forestier-Román, Ingrid S., et al.
Publicado: (2019)

Blockage of S100A8/A9 ameliorates septic nephropathy in mice
por: Shi, Wei, et al.
Publicado: (2023)

Cimifugin ameliorates imiquimod-induced psoriasis by inhibiting oxidative stress and inflammation via NF-κB/MAPK pathway
por: Liu, Aimin, et al.
Publicado: (2020)

Simvastatin Ameliorates Diabetic Cardiomyopathy by Attenuating Oxidative Stress and Inflammation in Rats
por: Al-Rasheed, Nawal M., et al.
Publicado: (2017)

Inhibition of AIM2 inflammasome-mediated pyroptosis by Andrographolide contributes to amelioration of radiation-induced lung inflammation and fibrosis
por: Gao, Jian, et al.
Publicado: (2019)

Oxymatrine Prevents NF-κB Nuclear Translocation And Ameliorates Acute Intestinal Inflammation
por: Guzman, Javier Rivera, et al.
Publicado: (2013)

Maslinic Acid Ameliorates Inflammation via the Downregulation of NF-κB and STAT-1
por: Lee, Wonhwa, et al.
Publicado: (2020)

Andrographolide sodium bisulfate attenuates UV-induced photo-damage by activating the keap1/Nrf2 pathway and downregulating the NF-κB pathway in HaCaT keratinocytes
por: Wang, Mei-Ling, et al.
Publicado: (2020)

Andrographolide Ameliorates Rheumatoid Arthritis by Regulating the Apoptosis–NETosis Balance of Neutrophils
por: Li, Xiaohong, et al.
Publicado: (2019)

Reaction Characteristics of Andrographolide and its Analogue AL-1 with GSH, as a Simple Chemical Simulation of NF-κB Inhibition
por: Yao, Hui, et al.
Publicado: (2012)

PAMs ameliorates the imiquimod-induced psoriasis-like skin disease in mice by inhibition of translocation of NF-κB and production of inflammatory cytokines
por: Dou, Rongkun, et al.
Publicado: (2017)

Kaempferol ameliorates Cisplatin induced nephrotoxicity by modulating oxidative stress, inflammation and apoptosis via ERK and NF-κB pathways
por: Wang, Zhu, et al.
Publicado: (2020)

Phillygenin inhibits inflammation in chondrocytes via the Nrf2/NF-κB axis and ameliorates osteoarthritis in mice
por: Zhang, Peng, et al.
Publicado: (2023)

Andrographolide contributes to spinal cord injury repair via inhibition of apoptosis, oxidative stress and inflammation
por: Li, Zhen, et al.
Publicado: (2022)

Blockage of NOX2/MAPK/NF-κB Pathway Protects Photoreceptors against Glucose Deprivation-Induced Cell Death
por: Fan, Bin, et al.
Publicado: (2017)

Amentoflavone ameliorates cold stress-induced inflammation in lung by suppression of C3/BCR/NF-κB pathways
por: Cai, Jiayi, et al.
Publicado: (2019)

Correction: PAMs ameliorates the imiquimod-induced psoriasis-like skin disease in mice by inhibition of translocation of NF-κB and production of inflammatory cytokines
por: Dou, Rongkun, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_tbg9bgr59gr3mg0fbh7ol7q26j