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Pbx loss in cranial neural crest, unlike in epithelium, results in cleft palate only and a broader midface
Orofacial clefting represents the most common craniofacial birth defect. Cleft lip with or without cleft palate (CL/P) is genetically distinct from cleft palate only (CPO). Numerous transcription factors (TFs) regulate normal development of the midface, comprising the premaxilla, maxilla and palatin...
Autores principales: | Welsh, Ian C., Hart, James, Brown, Joel M., Hansen, Karissa, Rocha Marques, Marcelo, Aho, Robert J., Grishina, Irina, Hurtado, Romulo, Herzlinger, Doris, Ferretti, Elisabetta, Garcia‐Garcia, Maria J., Selleri, Licia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6036936/ https://www.ncbi.nlm.nih.gov/pubmed/29797482 http://dx.doi.org/10.1111/joa.12821 |
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