Cargando…

Powerful anti-colon cancer effect of modified nanoparticle-mediated IL-15 immunogene therapy through activation of the host immune system

Rationale: Colorectal cancer (CRC) is the third most commonly diagnosed cancer around the world. Over the past several years, immunotherapy has demonstrated considerable clinical benefit in CRC therapy, and the number of immunologic therapies for cancer treatment continues to climb each year. Interl...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Xiaoxiao, Li, Yanyan, Sun, Xiaodong, Muftuoglu, Yagmur, Wang, Bilan, Yu, Ting, Hu, Yuzhu, Ma, Lu, Xiang, Mingli, Guo, Gang, You, Chao, Gao, Xiang, Wei, Yuquan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2018
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6037032/ https://www.ncbi.nlm.nih.gov/pubmed/30026861 http://dx.doi.org/10.7150/thno.24157

Ejemplares similares

Powerful anti-colon cancer effect of modified nanoparticle-mediated IL-15 immunogene therapy through activation of the host immune system: Erratum
por: Liu, Xiaoxiao, et al.
Publicado: (2019)

Powerful Anticolon Tumor Effect of Targeted Gene Immunotherapy Using Folate-Modified Nanoparticle Delivery of CCL19 To Activate the Immune System
por: Liu, Xiaoxiao, et al.
Publicado: (2019)

Self‐Assembled Bifunctional Peptide as Effective Drug Delivery Vector with Powerful Antitumor Activity
por: Fan, Rangrang, et al.
Publicado: (2017)

Aromatase inhibitors and antiepileptic drugs: a computational systems biology analysis
por: Muftuoglu, Yagmur, et al.
Publicado: (2011)

Prognostic immunogenic characteristics of iron pendant disease modifiers in colon cancer
por: Wang, Xian, et al.
Publicado: (2023)

Gene therapy for C-26 colon cancer using heparin-polyethyleneimine nanoparticle-mediated survivin T34A
por: Zhang, Ling, et al.
Publicado: (2011)

Co-Expression of Chicken IL-2 and IL-7 Enhances the Immunogenicity and Protective Efficacy of a VP2-Expressing DNA Vaccine against IBDV in Chickens
por: Huo, Shanshan, et al.
Publicado: (2019)

Cell-Based IL-15:IL-15Rα Secreting Vaccine as an Effective Therapy for CT26 Colon Cancer in Mice
por: Thi, Van Anh Do, et al.
Publicado: (2019)

Application of luteolin nanomicelles anti-glioma effect with improvement in vitro and in vivo
por: Zheng, Songping, et al.
Publicado: (2017)

Preparation, characterization and application of star-shaped PCL/PEG micelles for the delivery of doxorubicin in the treatment of colon cancer
por: Gao, Xiang, et al.
Publicado: (2013)

IL-15/IL-15Rα in SJS/TEN: Relevant Expression of IL15 and IL15RA in Affected Skin
por: Bellón, Teresa, et al.
Publicado: (2022)

Transcription Factors Associated With IL-15 Cytokine Signaling During NK Cell Development
por: Wang, Xiang, et al.
Publicado: (2021)

Prognostic role of Gli1 expression in breast cancer: a meta-analysis
por: Wang, Bilan, et al.
Publicado: (2017)

Safety and Immunogenicity of an HIV-1 Gag DNA Vaccine with or without IL-12 and/or IL-15 Plasmid Cytokine Adjuvant in Healthy, HIV-1 Uninfected Adults
por: Kalams, Spyros A., et al.
Publicado: (2012)

Improving anti-melanoma effect of curcumin by biodegradable nanoparticles
por: Wang, Bilan, et al.
Publicado: (2017)

Biodegradable and thermosensitive micelles inhibit ischemia-induced postoperative peritoneal adhesion
por: Wu, Qinjie, et al.
Publicado: (2014)

Comparison of three different diffractıve multifocal intraocular lenses with a +2.5, +3.0, and +3.75 diopter additıon power
por: Altinkurt, Emre, et al.
Publicado: (2019)

Combination therapy of RY10-4 with the γ-secretase inhibitor DAPT shows promise in treating HER2-amplified breast cancer
por: Su, Feng, et al.
Publicado: (2015)

Expression analysis of cytokines IL-5, IL-6, IL-8, IL-17 and VEGF in breast cancer patients
por: Liu, Gang, et al.
Publicado: (2022)

Low-dose immunogenic chemotherapeutics promotes immune checkpoint blockade in microsatellite stability colon cancer
por: Fang, Yuhang, et al.
Publicado: (2022)

Transgenic Expression of IL15 Retains CD123-Redirected T Cells in a Less Differentiated State Resulting in Improved Anti-AML Activity in Autologous AML PDX Models
por: Mu-Mosley, Hong, et al.
Publicado: (2022)

IL-15 superagonist/IL-15RαSushi-Fc fusion complex (IL-15SA/IL-15RαSu-Fc; ALT-803) markedly enhances specific subpopulations of NK and memory CD8+ T cells, and mediates potent anti-tumor activity against murine breast and colon carcinomas
por: Kim, Peter S., et al.
Publicado: (2016)

Applying an innovative biodegradable self-assembly nanomicelles to deliver α-mangostin for improving anti-melanoma activity
por: Yang, Shuping, et al.
Publicado: (2019)

Host discrimination of Mycoplasma pneumoniae proteinaceous immunogens
Publicado: (1983)

Delivery siRNA with a novel gene vector for glioma therapy by targeting Gli1
por: Zhou, Peizhi, et al.
Publicado: (2018)

Electrotransfer of IL-15/IL-15Rα complex for the treatment of established melanoma
por: Shirley, Shawna, et al.
Publicado: (2015)

An activation-induced IL-15 isoform is a natural antagonist for IL-15 function
por: Zhao, Lei, et al.
Publicado: (2016)

Electrotransfer of IL-15/IL-15Rα Complex for the Treatment of Established Melanoma
por: Shirley, Shawna A., et al.
Publicado: (2020)

Immunogenic chemotherapy in two mouse colon cancer models
por: Taniura, Takahito, et al.
Publicado: (2020)

Phenotype, Virulence and Immunogenicity of Edwardsiella piscicida Cyclic AMP Receptor Protein (Crp) Mutants in Catfish Host
por: Zhou, Peng, et al.
Publicado: (2020)

Co-expression IL-15 receptor alpha with IL-15 reduces toxicity via limiting IL-15 systemic exposure during CAR-T immunotherapy
por: Zhang, Ying, et al.
Publicado: (2022)

Multiple Perforations along the Entire Colon as a Complication of Intestinal Behcet's Disease: A Rare Case
por: Sekmen, Umit, et al.
Publicado: (2008)

Interleukin-15 (IL-15) and IL-15 receptor alpha fusion protein enhances antitumor activity of myxoma virus
por: Tosic, Vesna, et al.
Publicado: (2013)

IL-15 and IL15RA in Osteoarthritis: Association With Symptoms and Protease Production, but Not Structural Severity
por: Warner, Sophie C., et al.
Publicado: (2020)

Ultralow‐Power Machine Vision with Self‐Powered Sensor Reservoir (Adv. Sci. 15/2022)
por: Lao, Jie, et al.
Publicado: (2022)

Is the Host Viral Response and the Immunogenicity of Vaccines Altered in Pregnancy?
por: Saeed, Zainab, et al.
Publicado: (2020)

Immunogenic Cell Death Associated Molecular Patterns and the Dual Role of IL17RA in Interstitial Cystitis/Bladder Pain Syndrome
por: Zhang, Wei, et al.
Publicado: (2023)

Delivery of interleukin-22 binding protein (IL-22BP) gene by cationic micelle for colon cancer gene therapy
por: Men, Ke, et al.
Publicado: (2018)

Regulation of Antitumor Immune Responses by the IL-12 Family Cytokines, IL-12, IL-23, and IL-27
por: Xu, Mingli, et al.
Publicado: (2010)

Two Heme-Dependent Terminal Oxidases Power Staphylococcus aureus Organ-Specific Colonization of the Vertebrate Host
por: Hammer, Neal D., et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_cmjmffddt0nrutuf2tb53lptnu