CCR2-dependent monocytes/macrophages exacerbate acute brain injury but promote functional recovery after ischemic stroke in mice

Rationale: Peripheral blood monocytes are recruited into the ischemic brain and transform into macrophages after stroke. Nevertheless, the exact role of CCR2-dependent monocytes/macrophages in brain injury after stroke remains elusive. Methods: We used CCR2 knockout (KO) mice and the CCR2 pharmacolo...

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Detalles Bibliográficos
Autores principales: Fang, Weirong, Zhai, Xuan, Han, Dong, Xiong, Xiaoxing, Wang, Tao, Zeng, Xun, He, Shucheng, Liu, Rui, Miyata, Masaaki, Xu, Baohui, Zhao, Heng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6037034/
https://www.ncbi.nlm.nih.gov/pubmed/30026864
http://dx.doi.org/10.7150/thno.24475

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