Genome sequence of a multidrug-resistant Corynebacterium striatum isolated from bloodstream infection from a nosocomial outbreak in Rio de Janeiro, Brazil

Multidrug-resistant (MDR) Corynebacterium striatum has been cited with increased frequency as pathogen of nosocomial infections. In this study, we report the draft genome of a C. striatum isolated from a patient with bloodstream infection in a hospital of Rio de Janeiro, Brazil. The isolate presente...

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Detalles Bibliográficos
Autores principales: Ramos, Juliana Nunes, Rodrigues, Izabel dos Santos, Baio, Paulo Victor Pereira, Veras, João Flávio Carneiro, Ramos, Rommel Thiago Jucá, Pacheco, Luis GC, Azevedo, Vasco Ariston, Hirata, Raphael, Marín, Michel Abanto, de Mattos-Guaraldi, Ana Luiza, Vieira, Verônica Viana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Instituto Oswaldo Cruz, Ministério da Saúde 2018
Materias:
Genome Announcements and Highlights
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6037045/
https://www.ncbi.nlm.nih.gov/pubmed/29995109
http://dx.doi.org/10.1590/0074-02760180051
Descripción
Sumario:Multidrug-resistant (MDR) Corynebacterium striatum has been cited with increased frequency as pathogen of nosocomial infections. In this study, we report the draft genome of a C. striatum isolated from a patient with bloodstream infection in a hospital of Rio de Janeiro, Brazil. The isolate presented susceptibility only to tetracycline, vancomycin and linezolid. The detection of various antibiotic resistance genes is fully consistent with previously observed multidrug-resistant pattern in Corynebacterium spp. A large part of the pTP10 plasmid of MDR C. striatum M82B is present in the genome of our isolate. A SpaDEF cluster and seven arrays of CRISPR-Cas were found.

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