The Effect of Topoisomerase I Inhibitors on the Efficacy of T-Cell-Based Cancer Immunotherapy

BACKGROUND: Immunotherapy has increasingly become a staple in cancer treatment. However, substantial limitations in the durability of response highlight the need for more rational therapeutic combinations. The aim of this study is to investigate how to make tumor cells more sensitive to T-cell-based...

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Detalles Bibliográficos
Autores principales: McKenzie, Jodi A, Mbofung, Rina M, Malu, Shruti, Zhang, Min, Ashkin, Emily, Devi, Seram, Williams, Leila, Tieu, Trang, Peng, Weiyi, Pradeep, Sunila, Xu, Chunyu, Zorro Manrique, Soraya, Liu, Chengwen, Huang, Lu, Chen, Yuan, Forget, Marie-Andree, Haymaker, Cara, Bernatchez, Chantale, Satani, Nikunj, Muller, Florian, Roszik, Jason, Kalra, Ashish, Heffernan, Timothy, Sood, Anil, Hu, Jianhua, Amaria, Rodabe, Davis, R Eric, Hwu, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6037061/
https://www.ncbi.nlm.nih.gov/pubmed/29267866
http://dx.doi.org/10.1093/jnci/djx257

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