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Effects of Long-Term Denosumab on Bone Histomorphometry and Mineralization in Women With Postmenopausal Osteoporosis

CONTEXT: Denosumab is a potent antiresorptive agent that reduces fractures in postmenopausal women with osteoporosis. OBJECTIVE: Determine effects of up to 10 years of denosumab on bone histology, remodeling, and matrix mineralization characteristics. DESIGN AND SETTING: International, multicenter,...

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Detalles Bibliográficos
Autores principales: Dempster, David W, Brown, Jacques P, Fahrleitner-Pammer, Astrid, Kendler, David, Rizzo, Sebastien, Valter, Ivo, Wagman, Rachel B, Yin, Xiang, Yue, Susan V, Boivin, Georges
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6037073/
https://www.ncbi.nlm.nih.gov/pubmed/29672714
http://dx.doi.org/10.1210/jc.2017-02669