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Intratumor Heterogeneity of the Estrogen Receptor and the Long-term Risk of Fatal Breast Cancer
BACKGROUND: Breast cancer patients with estrogen receptor (ER)–positive disease have a continuous long-term risk for fatal breast cancer, but the biological factors influencing this risk are unknown. We aimed to determine whether high intratumor heterogeneity of ER predicts an increased long-term ri...
Autores principales: | Lindström, Linda S, Yau, Christina, Czene, Kamila, Thompson, Carlie K, Hoadley, Katherine A, van't Veer, Laura J, Balassanian, Ron, Bishop, John W, Carpenter, Philip M, Chen, Yunn-Yi, Datnow, Brian, Hasteh, Farnaz, Krings, Gregor, Lin, Fritz, Zhang, Yanhong, Nordenskjöld, Bo, Stål, Olle, Benz, Christopher C, Fornander, Tommy, Borowsky, Alexander D, Esserman, Laura J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6037086/ https://www.ncbi.nlm.nih.gov/pubmed/29361175 http://dx.doi.org/10.1093/jnci/djx270 |
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