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Immune-Active Microenvironment in Small Cell Carcinoma of the Ovary, Hypercalcemic Type: Rationale for Immune Checkpoint Blockade

Small cell carcinoma of the ovary, hypercalcemic type (SCCOHT), is a highly aggressive monogenic cancer driven by SMARCA4 mutations. Here, we report responses to anti-PD1 immunotherapy in four patients and characterize the immune landscape of SCCOHT tumors using quantitative immunofluorescence and g...

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Detalles Bibliográficos
Autores principales:	Jelinic, Petar, Ricca, Jacob, Van Oudenhove, Elke, Olvera, Narciso, Merghoub, Taha, Levine, Douglas A, Zamarin, Dmitriy
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2018
Materias:	Brief Communications
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6037122/ https://www.ncbi.nlm.nih.gov/pubmed/29365144 http://dx.doi.org/10.1093/jnci/djx277

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