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Vitamin D Levels of Out-Patients in Lithuania: Deficiency and Hypervitaminosis

Aim: Data on the prevalence of vitamin D deficiency in Lithuania are scarce. The aim was to assess the reserves of vitamin D in different age groups of out-patients, regarding the season of the year. Methods: Data on serum 25-hydroxyvitamin D (25(OH)D) levels from blood tests made in 2012–2014 were...

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Autores principales: Bleizgys, Andrius, Kurovskij, Jevgenij
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6037258/
https://www.ncbi.nlm.nih.gov/pubmed/30344256
http://dx.doi.org/10.3390/medicina54020025
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author Bleizgys, Andrius
Kurovskij, Jevgenij
author_facet Bleizgys, Andrius
Kurovskij, Jevgenij
author_sort Bleizgys, Andrius
collection PubMed
description Aim: Data on the prevalence of vitamin D deficiency in Lithuania are scarce. The aim was to assess the reserves of vitamin D in different age groups of out-patients, regarding the season of the year. Methods: Data on serum 25-hydroxyvitamin D (25(OH)D) levels from blood tests made in 2012–2014 were obtained from one laboratory, and a retrospective cross-sectional analysis was performed. Results: A total of 9581 subjects were included. The mean age of the participants was 33 ± 23 years. The mean levels of vitamin D were higher in males than in females (p < 0.001). The highest mean 25(OH)D levels were in 0–9-year-old group, the lowest were in the 10–19-year-old group and in the group of participants that were 70 years and older (p < 0.001). The lowest vitamin D status was found in January, February, March, and April. The highest status was found in August and September. Overall, vitamin D deficiency, sufficiency, and hypervitaminosis were detected in 67%, 21%, and 12% of cases, respectively. Most cases with hypervitaminosis were in the group of children up to 2 years of age. Conclusion: Vitamin D status demonstrated clear seasonality. Significant sex-related differences of vitamin D statuses were also determined. Vitamin D deficiency was very prevalent in almost all age groups. Young children (aged up to 2 years) are of special interest for further research involving other types of 25(OH)D assays, such as those based on high-performance liquid chromatography (HPLC), since the real prevalence of “true” vitamin D hypervitaminosis in Lithuania’s children is still to be determined.
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spelling pubmed-60372582018-10-18 Vitamin D Levels of Out-Patients in Lithuania: Deficiency and Hypervitaminosis Bleizgys, Andrius Kurovskij, Jevgenij Medicina (Kaunas) Article Aim: Data on the prevalence of vitamin D deficiency in Lithuania are scarce. The aim was to assess the reserves of vitamin D in different age groups of out-patients, regarding the season of the year. Methods: Data on serum 25-hydroxyvitamin D (25(OH)D) levels from blood tests made in 2012–2014 were obtained from one laboratory, and a retrospective cross-sectional analysis was performed. Results: A total of 9581 subjects were included. The mean age of the participants was 33 ± 23 years. The mean levels of vitamin D were higher in males than in females (p < 0.001). The highest mean 25(OH)D levels were in 0–9-year-old group, the lowest were in the 10–19-year-old group and in the group of participants that were 70 years and older (p < 0.001). The lowest vitamin D status was found in January, February, March, and April. The highest status was found in August and September. Overall, vitamin D deficiency, sufficiency, and hypervitaminosis were detected in 67%, 21%, and 12% of cases, respectively. Most cases with hypervitaminosis were in the group of children up to 2 years of age. Conclusion: Vitamin D status demonstrated clear seasonality. Significant sex-related differences of vitamin D statuses were also determined. Vitamin D deficiency was very prevalent in almost all age groups. Young children (aged up to 2 years) are of special interest for further research involving other types of 25(OH)D assays, such as those based on high-performance liquid chromatography (HPLC), since the real prevalence of “true” vitamin D hypervitaminosis in Lithuania’s children is still to be determined. MDPI 2018-04-26 /pmc/articles/PMC6037258/ /pubmed/30344256 http://dx.doi.org/10.3390/medicina54020025 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Bleizgys, Andrius
Kurovskij, Jevgenij
Vitamin D Levels of Out-Patients in Lithuania: Deficiency and Hypervitaminosis
title Vitamin D Levels of Out-Patients in Lithuania: Deficiency and Hypervitaminosis
title_full Vitamin D Levels of Out-Patients in Lithuania: Deficiency and Hypervitaminosis
title_fullStr Vitamin D Levels of Out-Patients in Lithuania: Deficiency and Hypervitaminosis
title_full_unstemmed Vitamin D Levels of Out-Patients in Lithuania: Deficiency and Hypervitaminosis
title_short Vitamin D Levels of Out-Patients in Lithuania: Deficiency and Hypervitaminosis
title_sort vitamin d levels of out-patients in lithuania: deficiency and hypervitaminosis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6037258/
https://www.ncbi.nlm.nih.gov/pubmed/30344256
http://dx.doi.org/10.3390/medicina54020025
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