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Vitamin D Levels of Out-Patients in Lithuania: Deficiency and Hypervitaminosis
Aim: Data on the prevalence of vitamin D deficiency in Lithuania are scarce. The aim was to assess the reserves of vitamin D in different age groups of out-patients, regarding the season of the year. Methods: Data on serum 25-hydroxyvitamin D (25(OH)D) levels from blood tests made in 2012–2014 were...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6037258/ https://www.ncbi.nlm.nih.gov/pubmed/30344256 http://dx.doi.org/10.3390/medicina54020025 |
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author | Bleizgys, Andrius Kurovskij, Jevgenij |
author_facet | Bleizgys, Andrius Kurovskij, Jevgenij |
author_sort | Bleizgys, Andrius |
collection | PubMed |
description | Aim: Data on the prevalence of vitamin D deficiency in Lithuania are scarce. The aim was to assess the reserves of vitamin D in different age groups of out-patients, regarding the season of the year. Methods: Data on serum 25-hydroxyvitamin D (25(OH)D) levels from blood tests made in 2012–2014 were obtained from one laboratory, and a retrospective cross-sectional analysis was performed. Results: A total of 9581 subjects were included. The mean age of the participants was 33 ± 23 years. The mean levels of vitamin D were higher in males than in females (p < 0.001). The highest mean 25(OH)D levels were in 0–9-year-old group, the lowest were in the 10–19-year-old group and in the group of participants that were 70 years and older (p < 0.001). The lowest vitamin D status was found in January, February, March, and April. The highest status was found in August and September. Overall, vitamin D deficiency, sufficiency, and hypervitaminosis were detected in 67%, 21%, and 12% of cases, respectively. Most cases with hypervitaminosis were in the group of children up to 2 years of age. Conclusion: Vitamin D status demonstrated clear seasonality. Significant sex-related differences of vitamin D statuses were also determined. Vitamin D deficiency was very prevalent in almost all age groups. Young children (aged up to 2 years) are of special interest for further research involving other types of 25(OH)D assays, such as those based on high-performance liquid chromatography (HPLC), since the real prevalence of “true” vitamin D hypervitaminosis in Lithuania’s children is still to be determined. |
format | Online Article Text |
id | pubmed-6037258 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-60372582018-10-18 Vitamin D Levels of Out-Patients in Lithuania: Deficiency and Hypervitaminosis Bleizgys, Andrius Kurovskij, Jevgenij Medicina (Kaunas) Article Aim: Data on the prevalence of vitamin D deficiency in Lithuania are scarce. The aim was to assess the reserves of vitamin D in different age groups of out-patients, regarding the season of the year. Methods: Data on serum 25-hydroxyvitamin D (25(OH)D) levels from blood tests made in 2012–2014 were obtained from one laboratory, and a retrospective cross-sectional analysis was performed. Results: A total of 9581 subjects were included. The mean age of the participants was 33 ± 23 years. The mean levels of vitamin D were higher in males than in females (p < 0.001). The highest mean 25(OH)D levels were in 0–9-year-old group, the lowest were in the 10–19-year-old group and in the group of participants that were 70 years and older (p < 0.001). The lowest vitamin D status was found in January, February, March, and April. The highest status was found in August and September. Overall, vitamin D deficiency, sufficiency, and hypervitaminosis were detected in 67%, 21%, and 12% of cases, respectively. Most cases with hypervitaminosis were in the group of children up to 2 years of age. Conclusion: Vitamin D status demonstrated clear seasonality. Significant sex-related differences of vitamin D statuses were also determined. Vitamin D deficiency was very prevalent in almost all age groups. Young children (aged up to 2 years) are of special interest for further research involving other types of 25(OH)D assays, such as those based on high-performance liquid chromatography (HPLC), since the real prevalence of “true” vitamin D hypervitaminosis in Lithuania’s children is still to be determined. MDPI 2018-04-26 /pmc/articles/PMC6037258/ /pubmed/30344256 http://dx.doi.org/10.3390/medicina54020025 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Bleizgys, Andrius Kurovskij, Jevgenij Vitamin D Levels of Out-Patients in Lithuania: Deficiency and Hypervitaminosis |
title | Vitamin D Levels of Out-Patients in Lithuania: Deficiency and Hypervitaminosis |
title_full | Vitamin D Levels of Out-Patients in Lithuania: Deficiency and Hypervitaminosis |
title_fullStr | Vitamin D Levels of Out-Patients in Lithuania: Deficiency and Hypervitaminosis |
title_full_unstemmed | Vitamin D Levels of Out-Patients in Lithuania: Deficiency and Hypervitaminosis |
title_short | Vitamin D Levels of Out-Patients in Lithuania: Deficiency and Hypervitaminosis |
title_sort | vitamin d levels of out-patients in lithuania: deficiency and hypervitaminosis |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6037258/ https://www.ncbi.nlm.nih.gov/pubmed/30344256 http://dx.doi.org/10.3390/medicina54020025 |
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