A Vascular-appearing Spindle Cell Xanthogranuloma in a Child

Spindle cell xanthogranuloma is a rare variant of juvenile xanthogranuloma that most commonly presents in adults as papulonodules. We describe a vascular-appearing case of spindle cell xanthogranuloma on the nose of a 10-year-old boy. The lesion was a dark red, well-demarcated, dome-shaped papule. H...

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Autores principales: Morse, Daniel C, Tschen, Jaime A, Migden, Micheal R, Silapunt, Sirunya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2018
Materias:
Dermatology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6037337/
https://www.ncbi.nlm.nih.gov/pubmed/30009107
http://dx.doi.org/10.7759/cureus.2595
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author Morse, Daniel C
Tschen, Jaime A
Migden, Micheal R
Silapunt, Sirunya
author_facet Morse, Daniel C
Tschen, Jaime A
Migden, Micheal R
Silapunt, Sirunya
author_sort Morse, Daniel C
collection PubMed
description Spindle cell xanthogranuloma is a rare variant of juvenile xanthogranuloma that most commonly presents in adults as papulonodules. We describe a vascular-appearing case of spindle cell xanthogranuloma on the nose of a 10-year-old boy. The lesion was a dark red, well-demarcated, dome-shaped papule. Histopathology revealed spindle-shaped histiocytes in a storiform pattern that stained positive for cluster of differentiation 68 (CD68) and the nuclear antigen Ki-67. No vascular features were found. To our knowledge, this is the first reported spindle cell xanthogranuloma to mimic an angiomatous lesion.
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spelling pubmed-60373372018-07-15 A Vascular-appearing Spindle Cell Xanthogranuloma in a Child Morse, Daniel C Tschen, Jaime A Migden, Micheal R Silapunt, Sirunya Cureus Dermatology Spindle cell xanthogranuloma is a rare variant of juvenile xanthogranuloma that most commonly presents in adults as papulonodules. We describe a vascular-appearing case of spindle cell xanthogranuloma on the nose of a 10-year-old boy. The lesion was a dark red, well-demarcated, dome-shaped papule. Histopathology revealed spindle-shaped histiocytes in a storiform pattern that stained positive for cluster of differentiation 68 (CD68) and the nuclear antigen Ki-67. No vascular features were found. To our knowledge, this is the first reported spindle cell xanthogranuloma to mimic an angiomatous lesion. Cureus 2018-05-08 /pmc/articles/PMC6037337/ /pubmed/30009107 http://dx.doi.org/10.7759/cureus.2595 Text en Copyright © 2018, Morse et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Dermatology
Morse, Daniel C
Tschen, Jaime A
Migden, Micheal R
Silapunt, Sirunya
A Vascular-appearing Spindle Cell Xanthogranuloma in a Child
title A Vascular-appearing Spindle Cell Xanthogranuloma in a Child
title_full A Vascular-appearing Spindle Cell Xanthogranuloma in a Child
title_fullStr A Vascular-appearing Spindle Cell Xanthogranuloma in a Child
title_full_unstemmed A Vascular-appearing Spindle Cell Xanthogranuloma in a Child
title_short A Vascular-appearing Spindle Cell Xanthogranuloma in a Child
title_sort vascular-appearing spindle cell xanthogranuloma in a child
topic Dermatology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6037337/
https://www.ncbi.nlm.nih.gov/pubmed/30009107
http://dx.doi.org/10.7759/cureus.2595
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