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PIK3CA mutations are specifically localized to lymphatic endothelial cells of lymphatic malformations
Lymphatic malformations (LM) are characterized by the overgrowth of lymphatic vessels during pre- and postnatal development. Macrocystic, microcystic and combined forms of LM are known. The cysts are lined by lymphatic endothelial cells (LECs). Resection and sclerotherapy are the most common treatme...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6037383/ https://www.ncbi.nlm.nih.gov/pubmed/29985963 http://dx.doi.org/10.1371/journal.pone.0200343 |