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The possibility of healing alveolar bone defects with simvastatin thermosensitive gel: in vitro/in vivo evaluation
BACKGROUND: In this study, simvastatin (SVT) in situ gels were successfully produced by our group. METHODS: The preparations were characterized in the following aspects: in vitro gelation, drug release, stability and pharmacodynamics. RESULTS: In this study, drug content of prepared gels was found t...
Autores principales: | Ruan, Hong, Yu, Youcheng, Guo, Xuehua, Jiang, Qian, Luo, Ying |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6037404/ https://www.ncbi.nlm.nih.gov/pubmed/30013319 http://dx.doi.org/10.2147/DDDT.S163986 |
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