Evolution of chemokine receptors is driven by mutations in the sodium binding site

Chemokines and their receptors (members of the GPCR super-family) are involved in a wide variety of physiological processes and diseases; thus, understanding the specificity of the chemokine receptor family could help develop new receptor specific drugs. Here, we explore the evolutionary mechanisms...

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Detalles Bibliográficos
Autores principales: Taddese, Bruck, Deniaud, Madeline, Garnier, Antoine, Tiss, Asma, Guissouma, Hajer, Abdi, Hervé, Henrion, Daniel, Chabbert, Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6037435/
https://www.ncbi.nlm.nih.gov/pubmed/29912865
http://dx.doi.org/10.1371/journal.pcbi.1006209

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6037435/
https://www.ncbi.nlm.nih.gov/pubmed/29912865
http://dx.doi.org/10.1371/journal.pcbi.1006209

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