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A meta-analysis of the antiviral activity of the HBV-specific immunotherapeutic TG1050 confirms its value over a wide range of HBsAg levels in a persistent HBV pre-clinical model
Pre-clinical models mimicking persistent hepatitis B virus (HBV) expression are seldom, do not capture all features of a human chronic infection and due to their complexity, are subject to variability. We report a meta-analysis of seven experiments performed with TG1050, an HBV-targeted immunotherap...
Autores principales: | Kratzer, Roland, Sansas, Benoît, Lélu, Karine, Evlachev, Alexei, Schmitt, Doris, Silvestre, Nathalie, Inchauspé, Geneviève, Martin, Perrine |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6037470/ https://www.ncbi.nlm.nih.gov/pubmed/29388874 http://dx.doi.org/10.1080/21645515.2018.1433970 |
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